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DPPH Free Radical Scavenging Effect of the Aerial Parts of Desmodium oldhami  

Yang, Seo-Kwon (College of Pharmacy, Woosuk University)
Park, Sae-Rom (College of Pharmacy, Woosuk University)
Ahn, Dal-Rae (College of Pharmacy, Woosuk University)
Yang, Jae-Heon (College of Pharmacy, Woosuk University)
Cho, Chong-Hyeon (Jeollabuk-do Agricultural Research and Extension Servieces)
Hwang, Yong-Hun (Kunbo Company)
Park, Jong-Han (Kunbo Company)
Kim, Dae-Keun (College of Pharmacy, Woosuk University)
Publication Information
Korean Journal of Pharmacognosy / v.41, no.3, 2010 , pp. 180-184 More about this Journal
Abstract
The antioxidant activity of Desmodium oldhami (Leguminosae) was determined by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl). The methanolic extract of D. oldhami showed the strong antioxidant activity. Five compounds, kaempferol-3-O-rhamnopyranoside (afzeline) (1), quercetin-3-O-[$\alpha$-L-rhamnopyranosyl($1{\rightarrow}6$)-$\beta$-Dglucopyranoside] (rutin) (2), kaempferol-3-O-glucopyranoside (astragalin) (3), genistein-7-O-$\beta$-D-glucopyranoside (genistin) (4), kaempferol-3-O-rutinoside (5) were isolated from the active ethyl acetate soluble fraction of D. oldhami through repeated silica gel and Sephadex LH-20 column chromatography. Among them, compound 2 showed the most significant antioxidative effect on DPPH free radical scavenging test. Compounds 1-5 are reported for the first time from this plant.
Keywords
Desmodium oldhami; Leguminosae; DPPH; Superoxide quenching activity;
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Times Cited By KSCI : 3  (Citation Analysis)
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