Browse > Article

Analysis and Stability Test of the Extract from Ephedrae Herba, Phytolaccae Radix and Polyporus for Toxicity Study  

Thao, Nguyen Thi Phuong (College of Pharmacy, Catholic University of Daegu)
Hung, Tran Manh (College of Pharmacy, Catholic University of Daegu)
Cuong, To Dao (College of Pharmacy, Catholic University of Daegu)
Huh, Jung-Im (Korea Institute of Toxicology)
Kwack, Seung-Jun (Department of Toxicological Research, National Institute of Toxicological Research)
Kim, Ji-Myoung (Department of Toxicological Research, National Institute of Toxicological Research)
Kang, Tae-Suk (Department of Toxicological Research, National Institute of Toxicological Research)
Lee, Je-Hyun (College of Oriental Medicine, Dongguk University)
Woo, Mi-Hee (College of Pharmacy, Catholic University of Daegu)
Choi, Jae-Sue (Faculty of Food Science and Biotechnology, Pukyoung National University)
Kang, Sam-Sik (College of Pharmacy, Seoul National University)
Bae, Ki-Hwan (College of Pharmacy, Chungnam National University)
Min, Byung-Sun (College of Pharmacy, Catholic University of Daegu)
Publication Information
Korean Journal of Pharmacognosy / v.41, no.2, 2010 , pp. 141-146 More about this Journal
Abstract
A simple and reliable reverse phase HPLC method was developed to determine pharmacologically active marker compounds of Ephedrae Herba, Phytolaccae Radix and Polyporus. The stability test of water-extract of three natural medicines were examined for six months. However, no significant change in the content of the marker compounds of each extract observed during the time of investigation.
Keywords
Ephedrae Herba; Phytolaccae Radix; Polyporus; Water-extract; Stability test; HPLC;
Citations & Related Records
Times Cited By KSCI : 4  (Citation Analysis)
Times Cited By SCOPUS : 0
연도 인용수 순위
1 Yamada, I., Takeucho, S., Oshima, S., Yoneyama, K., Shibuya, T., Kataoka, E., Segawa, D., Sato, W., Dohmen, T., Anezaki, Y., Ishii, H., and Ohnishi, H. (2008) Mao (Ephedra sinica Stapf) protects against D-galactosamine and lipopolysaccharide-induced hepatic failure. Cytokine 41: 293-301.   DOI   ScienceOn
2 Oh, Y. H., Lee, U. Y., Lee, M. W., Shim, M. J. and Lee, T. S. (2004) Immnuo-modulatory and Antitumor Effect of Crude Polysaccharides Extracted from Sclerotium of Grifolia umbellata. The Korean Journal of Mycology 32: 23-30.   과학기술학회마을   DOI   ScienceOn
3 Lee, Y. S., Kang, Y. H., Jung, J. Y., Lee, S., Ohuchi, K., Shin, K. H., Kang, I. J., Yoon-Park, J. H., Shin, H. K. and Lim, S. S. (2008) Protein Glycation Inhibitors from the fruiting body of Phelliuns linteus. Biol. Pharm. Bull. 31: 1968-1972.   DOI   ScienceOn
4 Nam, N. H., Lee, C. W., Hong, D. H., Kim, H. M., Bae, K. H. and Ahn, B. Z. (2003) Antiinvasive, antiangiogenic and antitumor activity of Ephedra sinica extract. Phytotherapy Research 17: 70-76.   DOI   ScienceOn
5 Jing, H., Luo, L., Sun, J., Yi, H., Wu, Y., Wang, C. and He, G. (2010) Ephedrine controls heart rhythms by activating cardiac I (ks) currents. J. Cardiovasc. Pharmacol. 55: 145-152.   DOI   ScienceOn
6 Jeong, H. S., Han, J. G., Ha, J. H., Kim, Y., Oh, S. H., Kim, S. S., Jeong, M. H., Choi, G. P., Park, U. Y. and Lee, H. Y. (2009) Enhancement of Anticancer Activities of Ephedra sinica, Angelica gigias by Ultra High Pressure Extraction. Korean J. Medicinal Crop Sci. 17: 102-108.   과학기술학회마을
7 Park, C. H. and Kwack, S. J. (2009) The effects of aristolochic acid on reproductive function in female rats. Kor. J. Pharmacogn. 40: 89-98.   과학기술학회마을
8 Won, K. H., Im, C. N., Choi, W. R., Lee, S. H., Cho, Y. S., Choi, S. E. and Kang, S. S. (1998) A case of Acute Renal Failure and Other Symptoms Associated with Phytolacca Radix Poisoning. The Korean J. Nephrology 17: 644-648.
9 편집부: 대한약전 (제8개정), 약업신문 (2002).
10 Kim, S. H., Choi, E. J., Kim, D. H., Lee, K. Y., Lee, M., Baek, S. W., Kwak, S. J., Kang, T. S., Kim, Y. C. and Sung, S. H. (2008) Stability test of the extracts of Cimicifugae Rhizoma, Achyranthis Radix, Artemisia Capillaris Herba, Moutan Cortex Radicis and Arecae Semen for toxicity study. Kor. J. Pharmacogn. 39: 241-245.   과학기술학회마을
11 Frei, H., Wurgler, F. E., Juon, H., Hall, C. B. and Graf, U. (1985) Aristolochic acid is mutagenic and recombinogenic in Drosophila genotoxicity tests. Arch. Toxicol. 56: 158-166.   DOI   ScienceOn
12 Mengs, U. (1987) Acute toxicity of aristolochic acid in rodents. Arch. Toxicol. 59: 328-331.   DOI   ScienceOn
13 Arlt, V. M., Annie, P. L., Cosyns, J. P. and Schmeiser, H. H. (2001) Analyses of DNA adducts formed by ochratoxin A and aristolochic acid in patiens with Chinese herbs nephropathy. Mutat. Res. 494: 143-150.   DOI   ScienceOn
14 식의약청고시 2003-17, 안전성유효성심사규정.
15 Zhao, Y. Y., Xie, R. M., Zhang, Y., Lin, R. C. and Sun, W. J. (2009) Bioactivity-directed isolation, identification of diurectic compounds from Polyporus umbellatus. J. Ethnopharmacol. 126: 184-187.   DOI   ScienceOn
16 Sun, Y. and Yasukawa, K. (2008) New anti-inflammatory ergostane-type ecdysteroids from the sclerotium of Polyporus umbellatus. Bioorg. Med. Chem. Lett. 18: 3417-3420.   DOI   ScienceOn
17 Ohsawa, T., Yukawa, M., Takao, C., Murayama, M. and Bando, H. (1992) Studies on constituents of fruit body of Polyporus umbellatus and their cytotoxic activity. Chem. Pharm. Bull. 40: 143-147.   DOI   ScienceOn
18 Tesra, M. L., Hajji, C., Zaballos-Garcia, E., Garcia-Segovia, A. B. and Sepulveda-Arques, J. (2001) Asymmetric synthesis of (-)-pseudoephedrine from (2S,3S)-3-phenyloxiran-2- ylmethanol. Stereospecific interchange of amino and alcohol functions. Tetrahedron: Asymmetry 12: 1369-1372.   DOI   ScienceOn
19 Drabowicz, J., Bujnicki, B., Biscarini, P. and Mikolajczyk, M. (1999) Diastereometric sulfinates derived from (L)-N-methylephedrine: synthesis, applications and rearrangements. Tetrahedron: Asymmetry 10: 3177-3187.   DOI   ScienceOn