Browse > Article

Development of the Standard Analytical Methods for Compound Hawthorn Berry 60% Ethanol Extract, Ginkgo Biloba Leaf Extract and Garlic Oil Capsules  

Cho, Chang-Hee (National Institute of Food and Drug Safety Evaluation)
Kim, Ji-Sun (Korea Food and Drug Administration)
Whang, Ji-Sang (National Institute of Food and Drug Safety Evaluation)
Baek, Ju-Hyun (Korea Food and Drug Administration)
Park, Ju-Young (National Institute of Food and Drug Safety Evaluation)
Shim, Young-Hoon (National Institute of Food and Drug Safety Evaluation)
Seong, Rack-Seon (National Institute of Food and Drug Safety Evaluation)
Kim, Dong-Sup (National Institute of Food and Drug Safety Evaluation)
Lee, Jong-Phill (Korea Food and Drug Administration)
Lee, Joo-Hyeun (Korea Food and Drug Administration)
Sohn, Su-Jung (National Institute of Food and Drug Safety Evaluation)
Publication Information
Korean Journal of Pharmacognosy / v.41, no.1, 2010 , pp. 67-72 More about this Journal
Abstract
In the recent version of the Korea Pharmacopoeia(KP) and the Korean Herbal Pharmacopoeia(KHP), there are 563 items(181 in KP, 381 in KHP) of herbal medicines including finished drugs. Also, approximately 507 items including herbal extracts and herbal medicinal products was published in the 3th edition of Korea Pharmaceutical Codex (KPC). These items help the persons working in the pharmaceutical manufacturing field to register the drug and in research fields to develop the new drug considering as a standard specifications. This study was carried out to establish standard analytical methods for 'Compound Hawthorn Berry 60% Ethanol Extract, Ginkgo Biloba Leaf Extract and Garlic Oil Capsules' in the 3th edition of Korea Pharmaceutical Codex. Ginkgo flavonoid and terpene lactone were employed as reference compounds for analytical method. Analytical methods established in this study could be applied to a reasonable and unified quality control of G. biloba leaf extract and hawthorn berry extract.
Keywords
Korean Pharmaceutical Codex; Compound Hawthorn Berry 60% Ethanol Extract; Ginkgo Biloba Leaf Extract and Garlic Oil Capsules; Hawthorn berry extract; Ginkgo biloba leaf extract; Melisa leaf extract; garlic oil;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By SCOPUS : 0
연도 인용수 순위
1 Kim, S. H., Kim, D.H., Park, J. H. and Sung, S. H. (2008) Development of the Standard Analytivcval Methods for Ginkgo biloba Leaf Extract, Kor. J. Pharmacogn. 39(3): 218-222.   과학기술학회마을
2 Kennedy, D. O., Scholey, A. B., Tildesley, N. T. J., Perry, E. K., Wesnes, K.A. (2002) Modulation of mood and cognitive performance following acute administration of Melissa officinalis (lemon balm), Pharmacol. Biochem. Behav. 72(4): 953-964.   DOI   ScienceOn
3 Ersoy, S., Orhan, I., Turan, N. N., Sahan, G., Ark, M. and Tosun F. (2008) Endothelium-dependent induction of vasorelaxation by Melissa officinalis L. ssp. officinalis in rat isolated thoracic aorta, Phytomedicine 15(12): 1087-1092.   DOI   ScienceOn
4 Bolkent, S., Yanardag, R., Karabulut-Bulan, O. and Yesilyaprak B. (2005) Protective role of Melissa officinalis L. extract on liver of hyperlipidemic rats: A morphological and biochemical study, J. Ethnopharmacol. 99(3): 391-398.   DOI   ScienceOn
5 Yao, M., Ritchie, H. E. and Brown-Woodman, P. D. (2008) A reproductive screening test of hawthorn. J. Ethnopharmacol. 118(1): 127-132.   DOI   ScienceOn
6 Long, S. R., Carey, R. A., Crofoot, K. M., Proteau, P. J. and Filtz, T. M. (2006) Effect of hawthorn (Crataegus oxycantha) crude extract and chromatographic fractions on multiple activities in a cultured cardiomyocyte assay. Phytomedicine 13(9-10): 643-650.   DOI   ScienceOn
7 Zhang, Z., Chang, Q., Zhu, M., Huang, Y., Ho, W. K. K. and Chen, Z. Y. Characterization of antioxidants present in hawthorn fruits (2001) J. Nutr. Biochem. 12(3): 144-152.   DOI   ScienceOn
8 Pittler, M., Schmidt, K. and Ernst, E. (2003) Hawthorn extract for treating chronic heart failure: meta-analysis of randomized trials. Am. J. Med. 114(8): 665-674.   DOI   ScienceOn
9 Liu, C. T., Hse, H., Lii, C. K., Chen, P. S. and Sheen, L. Y. (2005) Effects of garlic oil and diallyl trisulfide on glycemic control in diabetic rats, Eur. J. Pharmacol. 516(2): 165-173.   DOI   ScienceOn
10 Guginski, G., Luiz, A. P., Silva, M. D., Massaro, M., Martins, D. F., Chaves, J.. Mattos, R. W., Silveira, D., Ferreira, V. M. M., Calixto, J. B. and Santos, R. S. (2009) Mechanisms involved in the antinociception caused by ethanolic extract obtained from the leaves of Melissa officinalis (lemon balm) in mice, Pharmacol. Biochem. Beh. 93(1): 10-16.   DOI   ScienceOn
11 Liu, C. T., Wong, P. L., Lii, C. K., Hse, H. and Sheen, L. Y. (2006) Antidiabetic effect of garlic oil but not diallyl disulfide in rats with streptozotocin-induced diabetes, Food and Chem. Toxicol. 44(8): 1377-1384.   DOI   ScienceOn
12 Degenring, F. H., Suter, A., Weber, M. and Saller, R. (2003) A randomised double blind placebo controlled clinical trial of a standardised extract of fresh Crataegus berries (Cratae-gisan${\circledR}$) in the treatment of patients with congestive heart failure NYHA II, Phytomedicine 10(5): 363-369.   DOI   ScienceOn
13 식품의약품안전청 (2007) 의약품등기준및시험방법 제2개정 추보2.
14 Jamison, J. (2003) Hawthorn (Crataegus oxyacantha), Clinical Guide to Nutrition & Dietary Supplements in Disease Management 569-572.