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Quantitative Analysis of Chemical Constituents in Psoraleae Semen and the Processed Psoraleae Semen  

Kim, Yu-Jin (School of Biotechnology, Yeungnam University)
Shim, Sang-Hee (School of Biotechnology, Yeungnam University)
Publication Information
Korean Journal of Pharmacognosy / v.41, no.1, 2010 , pp. 54-57 More about this Journal
Abstract
A reversed phase HPLC method was developed to determine the major components of Psoralea corylifolia, psoralen, isopsoralen, bakuchiol, and corylin. Quantitative analysis of the above compounds was performed by C-18 column using a gradient solvent system of acetonitrile and water with UV detection at 310 nm. The comparison of contents of psoralen, isopsoralen, bakuchiol, and corylin in psoraleae semen and the processed psoraleae semen was also investigated. In result, processed psoraleae semen showed more amounts of psoralen, isopsoralen, and corylin with 1.6, 4.3, and 1.3 mg/g, respectively, except bakuchiol (66.98 mg/g) while psoraleae semen showed 0.53, 1.56, 1.0, and 76.3 mg/g of psoralen, isopsoralen, corylin, and bakuchiol, respectively.
Keywords
Psoralea corylifolia; quantitative analysis; HPLC; contents;
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1 Kim, Y. J., Lee, H. Park, E. and Shim, S. H. (2009) Inhibition of Human 20S Proteasome by Compounds from Seeds of Psoralea corylifolia. Bull. Korean Chem. Soc. 30(8): 1867-1869.   DOI   ScienceOn
2 Shim, S. H. (2008) Proteasome Inhibition Activity of Psoraleae Semen and Processed Psoraleae Semen. Kor. J. Pharmacogn. 39(1): 56-59.   과학기술학회마을
3 Mehta, G., Nayak, U. R. and Dev, S. (1973) Meroterpenoids: Psoralea corylifolia Linn.-l. Bakuchiol, a novel monoterpene phenol. Tetraheron 29: 1119-1125.   DOI   ScienceOn
4 Dong, N. T., Bae, K. H., Kim, Y. H., Hwang, G. S., Hwang, O. S., Kim, S. E. and Jong Seong Kang (2003) Quantitative determination of psoralen and angelicin from some medicinal herbs by high performance liquid chromatography. Arch. Pharm. Res. 26(7): 516-520.   과학기술학회마을   DOI   ScienceOn
5 Yang, B., Yai, S. and Cui, S. (1996) Comparison of ancient and modern processing methods for fructus Psoraleae, Zhongguo Zhong Yao Za Zhi 21(9): 537-539.
6 Tan, S., Wang, Y., Liu, G., Guo, D. and Han, J. (1995) Determination of psoralen and isopsoralen in tincture of fructus Psoraleae by HPLC. Zhongguo Zhong Yao Za Zhi 20(2): 99-100.
7 Kim, H. K., Lee, H. W., Chun, J. M., Lee, A. Y. and Ko, B. S. (2004) Quantitative Analysis of Psoralen and Angelicin in the Psoraleae Semen and Processed Psoraleae Semen. Kor. J. Pharmacogn. 35(3): 179-183.   과학기술학회마을
8 Jiangsu New Medical College (1985) Dictionary of Traditional Chinese Herbs, 1178. Shanghai Science and Technology Publishing House, Shanghai.
9 Wang, S. (2006) Research survey of pharmacological effects of Fructus Psoraleae. Shizhen Guoyi Guoyao 17: 1081-1082.
10 신문농출판공가 (1995) 중약대사전, 2782. 일중사, 서울.
11 Suri, J. L., Gupta, G. K., Dhar, K. L. and Atal, C. K. (1978) Psoralenol: A new isoflavone from the seeds of Psoralea corylifolia. Phytochemistry 17: 2046.   DOI   ScienceOn
12 Khastgir, H. N., Duttagupta, P. C. and Sengupta, P. (1961) The structure of psoralidin. Tetrahedron 14: 275-283.   DOI   ScienceOn
13 Gupta, G. K., Dhar, K. L. and Atal, C. K. (1978) Corylinal: A new isoflavone from seeds of Psoralea corylifolia. Phytochemistry 17: 164.   DOI   ScienceOn