Anti-hyperlipidemic Effects of the Flavonoid-rich Fraction from the Methanol Extract of Orostachy japonicus in Rats
![]() ![]() |
Kim, Sei-Gun
(Department of Oriental Pharmacy and Wonkwang-Oriental Medicines Research Institute, Wonkwang University)
Choi, Jong-Won (College of Pharmacy, Kyungsung University) Park, Hee-Juhn (Department of Pharmaceutical Engineering, Sangji University) Lee, Sang-Myung (KT&G Central Research Institute) Jung, Hyun-Ju (Department of Oriental Pharmacy and Wonkwang-Oriental Medicines Research Institute, Wonkwang University) |
1 | Surprenant, Y. M. and Zuckerman, S. H. (1989) A novel microtiter plate assay for the quantitation of procoagulant activity on adherent monocytes, macrophages and endothelial cells. Thromb. Res. 53: 339-346 DOI ScienceOn |
2 | Jo, H. S. (2004) Protective Mechanism of Flavonoid Isolated from Rhus verniciflua Stokes on the Paraquat Toxicity and Hyperlipidemic Diet in Rats. Ph. D. Thesis in Department of Pharmacy Graduate School Kyungsung University, 54-64 |
3 | Park, H. J., Nam, J. H., Jung, H. J., Lee, M. S., Lee, K. T., Jung, M. H. and Choi, J. W. (2005) Inhibitory effect of euscaphic acid and tormentic acid from the Roots of Rosa urgosa on high fat diet induced obesity. Kor. J. Pharmacogn. 36: 324-331 |
4 | Moon, H. S., Lee, H. G., Choi, Y. J., Kim, T. G. and Cho, C. S. (2007) Proposed mechanism of (-)-epigallocatechin-3-gallate for anti-obesity. Chem. Biol. Interact. 167: 85-98 DOI ScienceOn |
5 | McGowan, M. W., Artiss, J. D. and Strandbergh, D. R. (1983) A peroxidase-coupled method for the colorimetric determination of serum triglycerides. Clin. Chem. 29: 538-542 PUBMED ScienceOn |
6 | Kobatake, Y., Saito, M., Kurda, K., Kobayashi, S. and Innami, S. (1987) Influence of fish consumption on serum lipid and lipid peroxide concentrations in middle aged subjects. J. Japan Soc. Nutr & Food Sci. 40: 103-107 DOI |
7 | Oyanagui, Y. (1984) Reevaluation of assay methods and establishment of Kit for superoxide dismutase activity. Anal. Biochem. 42: 290-296 |
8 | Berenice, C. W., Michel, V., Allain, F., Catherine, G., Veronique, K., Josianne, A. and Marie, J. R. (1992) Selenium, glutathione peroxidase and lipid peroxidation products before and after selenium supplementation. Clin. Chim. Acta. 207: 137-142 DOI PUBMED ScienceOn |
9 | Aebi, H. (1974) Catalase in method of enzymatic analysis. Academic press (New York) 2: 673-675 |
10 | Han, Y. N., Baik, S. K., Kim, T. H and Han, B. H. (1987) Antithrombotic Activities of Saponins from Ilex pubescens. Arch. Pharm. Res. 10: 115-120 DOI ScienceOn |
11 | Jung, H. J., Choi, J., Nam, J. H., Park, H. J. (2007) Antiulcerogenic effects of the flavonoid-rich fraction from the extract of Orostachys japonicus in mice. J. Med. Food 10: 702-706 DOI ScienceOn |
12 | Park, H. J., Moon, S. H., Kim, J. O., Lee, S. H. and Choi, J. S. (1991) A study on the chemical constituents of Orostachys japonicus A Berger, Kor. J. Pharmacogn 22: 78-84 과학기술학회마을 |
13 | 특허청 (2008) 살빼는 약도 천연물 이용 활발, Patent |
14 | Yagi, K. (1987) Lipid peroxides and human diseases. Chem. Phys. Lipids. 45: 337-351 DOI ScienceOn |
15 | Park, H. J., Young, H. S., Park, K. Y., Rhee, S. H., Chung, H. Y. and Choi J. S. (1991) Flavonoids from the Whole Plants of Orostachys japonicus, Arch. Pharm. Res. 14: 167-171 DOI ScienceOn |
16 | Ven Gent, C. M. and Roseleur, O. J. (1974) Quantitative determination of phospholipids in blood serum or plasma by a nondestructive method, Clin. Chim. Acta. 57: 197-203 DOI ScienceOn |
17 | Richard, W. (1976) Use of cholesterol oxidase for assay of total and free cholesterol in serum by continuous flow anlysis. Clin. Chem. 22: 1579-1588 PUBMED ScienceOn |
18 | Gatecki, P., Pietras, T. and Florkowki, A. (2005) Pro- and antioxidant processes in schizophrenics with tardive dyskinesia. Psychiatr Pol. 39: 1131-1141 PUBMED ScienceOn |
19 | Lowry, O. H., Rosebrough, N. J., Farr, A. L. and Rendall, R. J. (1951) Protein Measurement with folin phenol reagent. J. Biol. Chem. 256: 9994-9998 DOI |
20 | Jung, H. J., Nam, J. H., Park, H. J., Lee, K. T., Park, K. K., Kim, W. B. and Choi, J. (2007) The MeOH extract of Pleurospermum kamtschaticum and its active component buddlejasaponin inhibits intrinsic and extrinsic hyperlipidemia and hypercholesterolemia in the rat. J. Ethnopharmacol. 112: 255-261 DOI ScienceOn |
![]() |