Browse > Article

Antibacterial Compounds of the Root Barks of Cudrania tricuspidata  

Kim, Youn-Chul (College of Pharmacy, Wonkwang University)
Hur, Jin (College of Pharmacy, Wonkwang University)
Sohn, Dong-Hwan (College of Pharmacy, Wonkwang University)
Kim, Hak-Sung (College of Pharmacy, Wonkwang University)
Publication Information
Korean Journal of Pharmacognosy / v.39, no.3, 2008 , pp. 246-248 More about this Journal
Abstract
Six prenylated xanthones, cudraxanthone B (1), isocudraxanthone K (2), cudraxanthone H (3), cudratricusxanthone A (4), cudraxanthone L (5) and macluraxanthone B (6), have been isolated from the MeOH extract of Cudrania tricuspidata root barks. The evaluation for antibacterial effect of compounds 1-6 against the pathogenic microorganisms concerning with public health or zoonosis was conducted. Of these, compound 4 showed significant antibacterial effect in disk diffusion method.
Keywords
Cudrania tricuspidata; Moraceae; Prenylated xanthones; Antibacterial;
Citations & Related Records

Times Cited By SCOPUS : 0
연도 인용수 순위
  • Reference
1 Jennison, A. V. and Verma, N. K. (2004) Shigella flexneri infection: pathogenesis and vaccine development. FEMS Microbiol. Rev. 28: 43-58   DOI   ScienceOn
2 Groweiss, A., Cardellina, J. H. and Boyd, M. R. (2000) HIV-inhibitory prenylated xanthones and flavones from Maclura tinctoria. J. Nat. Prod. 63: 1537-1539   DOI   ScienceOn
3 Fujimoto T., Hano Y., Nomura T. and Uzawa J. (1984) Components of root bark of Cudrania tricuspidata 2. Structures of two new isoprenylated flavones, cudraflavones A and B. Planta. Med. 50: 161-163   DOI   ScienceOn
4 Jiang su new medical college (1977) Encyclopedia of Chinese Medicinal Substances. Shanghai Peoples Publisher, Shanghai, p. 1502
5 An, R. B., Sohn, D. H. and Kim, Y. C. (2006) Hepato-protective compounds of the roots of Cudrania tricuspidata on tacrine-induced cytotoxicity in Hep G2 cells. Biol. Pharm. Bull. 29: 838-840   DOI   ScienceOn
6 Jin, L. Z., Samuel, K. B., Ronald, R. M. and Andrew, A. F. (1998) In vitro inhibition of adhesion of enterotoxigenic Esxherichia coli K88 to piglet intestinal mucus by egg-yolk antibodies. FEMS Immunol. Med. Mic. 21: 313-321   DOI
7 Barbour, E. K., Al Sharif, M., Sagherian, V. K., Habre, A. N., Talhouk, R. S. and Talhouk, S. N. (2004) Screening of selected indigenous plants of Lebanon for antimicrobial activity. J. Ethnopharmacol. 93: 1-7   DOI   ScienceOn
8 Hano, Y., Matsumoto, Y., Sun, J. Y. and Nomura, T. (1990) Structures of four new isoprenylated xanthones, cudraxanthones h, i, j, and k. Planta. Med. 56: 478-481   DOI   ScienceOn
9 Tiemersma, E. W., Bronzwaer, S. L., Lytikainen, O., Degener, J. E., Schrijnemakers, P., Bruinsma, N., Monen, J., Witte, W. and Grundman, H. (2004) Methicillin-resistant Staphylococcus aureus in Europe, 1999-2002. Emerg. Infect. Dis. 10: 1627-1634   DOI   ScienceOn
10 Zou, Y. S., Hou, A. J., Zhu, G. F., Chen, Y. F., Sun, H. D. and Zhao, Q. S. (2004) Cytotoxic isoprenylated xanthones from Cudrania tricuspidata. Bioorg. Med. Chem. 12: 1947-1953   DOI   ScienceOn
11 Mead, P. S. and Griffin, P. M. (1998) Escherichia coli O157:H7. Lancet 352: 1207-1212   DOI   ScienceOn
12 Hano, Y., Matsumoto, Y., Shinohara, K., Sun, J. Y. and Nomura, T. (1991) Structures of four new isoprenylated xanthones, cudraxanthones L, M, N, and O from Cudrania tricuspidata. Planta. Med. 57: 172-175   DOI   ScienceOn