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Changes in Chemical Composition and Biological Activities of Oriental Crude Drugs by Food Processing Techniques IV - Increase in 5-HMF Content of Aurantii nobilis Pericarpium During Roasting Process -  

Ni, Qinxue (School of Applied Life Sciences, College of Agriculture and Life Sciences, Kyungpook National University)
Hur, Jong-Moon (School of Applied Life Sciences, College of Agriculture and Life Sciences, Kyungpook National University)
Choi, Sun-Ha (School of Applied Life Sciences, College of Agriculture and Life Sciences, Kyungpook National University)
Yang, Eun-Ju (School of Applied Life Sciences, College of Agriculture and Life Sciences, Kyungpook National University)
Lee, Yu-Mi (Department of Genetic Engineering, College of Natural Sciences, Kyungpook National University)
Kang, Young-Hwa (School of Applied Life Sciences, College of Agriculture and Life Sciences, Kyungpook National University)
Song, Kyung-Sik (School of Applied Life Sciences, College of Agriculture and Life Sciences, Kyungpook National University)
Publication Information
Korean Journal of Pharmacognosy / v.38, no.2, 2007 , pp. 133-138 More about this Journal
Abstract
Regarding chemical changes in oriental drugs after food processing such as roasting, fermentation, and extrusion, fifty commonly-used medicinal plants were investigated. As a result, Aurantii nobilis Pericarpium (a tangerine peel from Citrus unshu Markovich) showed remarkably different HPLC profiles after being roasted. An increased peak was isolated by repeated chromatography and identified as 5-hydroxymethyl furfral (5-HMF) by means of instrumental analyses. The 5-HMF content of Aurantii nobilis Pericarpoum reached its maximum level after being roasted for 30 min at 225$^{\circ}C$ (49.2 mg/g extract, ca 42 times of increase over untreated control). Although there were no significant changes in in vitro biological activity such as antioxidative, anti-dementia, anti-hypertension, anti-coagulation, or cytotoxicity, before and after roasting process, our results suggested that simple heat treatment might improve the value of the above oriental drug since 5-HMF has been known to possess inhibitory activities toward nitric oxide formation, tyrosinase, and sickling of red blood cells.
Keywords
Aurantii nobilis Pericarpoum; roasting; processing; 5-Hydroxymethyl furfural (5-HMF);
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Times Cited By KSCI : 6  (Citation Analysis)
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