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Isolation and Quantitative Determination Method Validation of myristicin from Myristica fragrans Houttuyn  

Kim, Soo-Hwan (Analytical Science Center, Samyang Medical R&D Center)
Lee, Dong-Ho (Analytical Science Center, Samyang Medical R&D Center)
Kwon, Soo-Han (Department of Chemistry, Chungbuk National University)
Lim, Buyng-Ho (Analytical Science Center, Samyang Medical R&D Center)
Lee, Sang-Hun (Analytical Science Center, Samyang Medical R&D Center)
Min, Bum-Chan (Analytical Science Center, Samyang Medical R&D Center)
Publication Information
Korean Journal of Pharmacognosy / v.38, no.1, 2007 , pp. 19-21 More about this Journal
Abstract
Myristica fragrans has been used for the treatment of stomachache in East Asia. It is very important to determine the amount of myristicin in Myristica fragrans, because excess myristicin causes side effects. In this study, we developed and validated the method for determination contents of myristicin in Myristica fragrans which was purchased from various regions of Korea. The average content of myristicin in Myristica fragrans was 2.10% with the validated HPLC analysis method.
Keywords
Myristicin; Myristica fragrans; quantitative analysis; validation;
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Times Cited By SCOPUS : 3
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