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Hepatoprotective Effects of Brassica rapa (Turnip) on d-Galactosamine Induced Liver Injured Rats  

Choi, Hyuck-Jae (East-West Medical Research Institute, Kyung Hee University)
Han, Myung-Joo (Department of Food and Nutrition, Kyung Hee University)
Baek, Nam-In (Graduate School of Biotechnology and Plant Metabolism Research Center, Kyung Hee University)
Kim, Dong-Hyun (College of Pharmacy, Kyung Hee University)
Jung, Hae-Gon (Ganghwa Argicultural R&D Center)
Kim, Nam-Jae (East-West Medical Research Institute, Kyung Hee University)
Publication Information
Korean Journal of Pharmacognosy / v.37, no.4, 2006 , pp. 258-265 More about this Journal
Abstract
Brassica rapa L. (Turnip) which is one of the specialized crops in Ganghwa island, has been used for diuretic, digestive, and curative for jaundice, etc. In this study, the anti oxidative effects and hepatoprotective effects of turnip in vitro and in vivo were investigated in order to evaluate the possibility as hepatoprotective agents. Ethanol extract of turnip potently showed the scavenging effect on DPPH and inhibitory effect on lipid peroxidation. Oral administration of turnip extract to dgalactosamine-induced experimental liver injured rats was significantly reduced the serum AST, ALT and LDH enzyme activities. And the decrease of catalase and SOD activities in liver microsolmal cytosol was significantly improved by the treatment of turnip. Based on these findings, it is presumed that ethanol extract of turnip may have the hepatoprotective effect on d-galactosamine-induced hepatotoxicity rat.
Keywords
Brassica rapa; Turnip; anti oxidative activity; hepatoprotective effects; transaminase activities; SOD; catalse;
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