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Standardization of Morinda officinalis How  

Lee, Hye-Won (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Park, So-Young (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Choo, Byung-Kil (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Chun, Jin-Mi (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Lee, A-Yeong (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Kim, Ho-Kyoung (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Publication Information
Korean Journal of Pharmacognosy / v.37, no.4, 2006 , pp. 241-245 More about this Journal
Abstract
Morinda officinalis How. (Rubiaceae) has been used as tonic, warming, sex impulse and anti-inflammatory agents. Two known anthraquinones, rubiadin-1-methyl ether (I) and rubiadin (II) were isolated from root of M. officinalis. Their structures were identified using NMR and literature comparisons. The contents of I in eighteen M. officinalis were evaluated by HPLC-PDA. Chromatography was performed using a reversed-phase system with Luna $C_{18}$ (2) column and acetonitrile-water (50:50, v/v) with a flow rate of 1.0 mL/min under UV 280 nm. Under these conditions, the content of rubiadin-1-methyl ether was 0.013%.
Keywords
Morinda officinalis How.; rubiadin; rubiadin-1-methyl ether; HPLC-PDA;
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