Browse > Article

Constituents from Hypericum ascyron  

Chae, Sung-Wook (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Lee, So-Young (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Kim, Ju-Sun (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Bae, Ki-Hwan (College of Pharmacy, Chungnam National University)
Kim, Sung-Kyu (Vitaminhouse R&BT)
Kang, Sam-Sik (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Publication Information
Korean Journal of Pharmacognosy / v.37, no.3, 2006 , pp. 162-168 More about this Journal
Abstract
The isolation and identification of a new xanthone (6-0-palmitolyl-1,6-dihydroxy-5,7-dimethoxyxanthone) along with n-alkanols, fatty acids, 1,6-dihydroxy-5,7-dimethoxyxanthone, 1,7-dihydroxykanthone, betulinic acid, ${\beta}-sitosterol$, methyl 4-hydroxybenzoate, quercetin, and kaempferol from the aerial parts of Hypericum ascyron was reported. The structures were elucidated by spectroscopic methods, mainly NMR and mass spectrometry.
Keywords
Hypericum ascyron; Guttiferae; isolation and identification;
Citations & Related Records

Times Cited By SCOPUS : 0
연도 인용수 순위
  • Reference
1 Ebadi, M. (2002) Phannacodynamic Basis of Herbal Medicine. 2nd Ed., 457-470, CRC Press, Boca Raton
2 Wang, Z. Q. and Wang, X. R. (1980) Studies on the Constituents of Hong Han Lian (Hypericum ascyron L.). Acta Pharm. Sin. 15: 365-367
3 Don, M.-J, Huang, Y.-J, Huang, R.-L. and Lin, Y.-L. (2004) New Phenolic Principles from Hypericum sampsonii. Chem. Pharm. Bull. 52: 866-869   DOI   ScienceOn
4 Cardona, M. L., Fernandez, M. I., Pedro, J. R., Seoane, E. and Vidal, R. (1986) Additional New Xanthones and Xanthonolignoids from Hypericum canariensis. J Nat. Prod. 49: 95-100   DOI
5 Gunatilaka, A. A. L., De Silva, A M. Y. J. and Sotheeswaran, S. (1982) Minor Xanthones of Hypericum mysorense. Phytochemistry 21: 1751-1753   DOI
6 Luo, L., Sun, Q., Mao, Y. Y., Lu, Y. H. and Tan, R. X. (2004) Inhibitory effects of flavonoids from Hypericum perforatum on nitric oxide synthase. J. Ethnopharmacol. 93: 221-225   DOI   ScienceOn
7 Chen, M.-T., Kuoh, Y.-P., Wang, C.-H., Chen, C.-M. and Kuoh, C.-H. (1989) Additional Constituents of Hypericum subalatum. J. Chin. Chem. Soc. 36: 165-168   DOI
8 EI-Seedi, H. R., Ringbom, T., Torssell, K. and Bohlin, L. (2003) Constituents of Hypericum laricifolium and Their Cyclooxygenase (COX) Enzyme Activities. Chem. Pharm. Bull. 51: 1439-1440   DOI   ScienceOn
9 Lin, C.-N., Chung, M.-I., Lion, S.-J., Lee, T.-H. and Wang, J.-P. (1996) Synthesis and Anti-inflammatory Effects of Xanthone Derivatives. J. Pharm. Pharmacol. 48: 532-538   DOI   ScienceOn
10 Hu, L.-P., Yip, S.-C. and Sim, K.-Y. (1999) Xanthones from Hypericum ascyron. Phytochemistry 52: 1371-1373   DOI   ScienceOn
11 Chen, M.-T., Wang, C.-H., Chen, C.-M. and Kuoh, C.-S. (1988) Flavonoids from Hypericum nagasawai Hayata. J. Chin. Chem. Soc. 35: 167-172   DOI
12 배기환 (2000) 한국의 약용식물, 176, 교학사, 서울
13 Cardona, M. L. and Seoane, E. (1982) Xanthone Constituents of Hypericum ericoides. J. Nat. Prod. 45: 134-136   DOI
14 McKenna, D. J., Jones, K. and Hughes, K. (2002) Botanical Medicines. The Desk Reference for Major Herbal Supplements. 2nd Ed., 923-986, The Haworth Herbal Press, New York
15 Hong, D., Yin, F., Hu, L.-H. and Lu, P. (2004) Sulfonated xanthones from Hypericum sampsonii. Phytochemistry 65:2595-2598   DOI   ScienceOn
16 Mu, Q., Gibbons, S., Stavri, M., Smith, E., Zhou, F.-S. and Hu, C.-Q. (2006) Antibacterial Effects ofHypericum ascyron and Hypericum japonicum against Multidrug-Resistant Staphylococcus aureus. Pharm. Biol. 44: 157-159   DOI   ScienceOn
17 Alves de Lima, R., Gottlieb, O. R. and Lins Mesquita, A. A. (1972) Xanthones from Caraipa densiflora. Phytochemistry 11: 2307-2309   DOI   ScienceOn
18 이창복 (1989) 대한식물도감, 544-546, 향문사, 서울
19 정칠만, 황은주, 권학철, 김선여, 배기환, 지옥표, 이강노 (1996) 고추나물의 항산화 활성 Flavonoid성분, 생약학회지 30: 196-201
20 Zou, Y.-P., Lu, Y.-H. and Wei, D.-Z. (2004) Antioxidative Activity of a Flavonoid-rich Extract of Hypericum perforatum L. in Vitro. J Agric. Food Chem. 52; 5023-5039
21 Gamiotea-Turro, D., Cuesta-Rubio, O., Prieto-Gonzalez, S., De Simone, F., Passi, S. and Rastrelli, L. (2004) Antioxidative Constituents from the Leaves of Hypericum styphelioides. J Nat. Prod. 67: 869-871   DOI   ScienceOn
22 Ross, I. A. (2001) Medicinal Plants of the World. Vol. 2, Chemical Constituents, Traditional and Modem Medicinal Uses. Humana Press, Totowa, New Jersey
23 Locksley, H. D., Moore, I. and Scheinmann, F. (1966) Extractives from Guttiferae. Part II. The Isolation and Structure of Four Polyhydroxyxanthones in Symphonia globulifera L. J. Chem. Soc. (C) 430-432
24 Jiang Su New Medical College (1977) Dictionary of Chinese Crude Drugs. Shanghai Scientific Technological Publishers, Shanghai
25 WU, Q.-L., Wang, S.-P., Yang, J.-S. and Xiao, P.-G. (1998) Xanthones from Hypericum japonicum and H. henryi. Phytochemistry 49: 1395-1402   DOI   ScienceOn
26 Kijjoa, A, Jose, M., Gonzalez, T. G, Pinto, M. M. M., Damas, A.M., Mondranondra, I., Silva, A. M. S. and Herz, W. (1998) Xanthones from Cratoxylum maingayi. Phytochemistry 49: 2159-2162   DOI   ScienceOn
27 Cakir, A., Mavi, A, Yldrm, A., Duru, M. E., Harmandar, M. and Kazaz, C. (2003) Isolation and characterization of antioxidant phenolic compounds from the aerial parts of Hypericum hyssopifolium L. by activity-guided fractionation. J. Ethnopharmacol. 87: 73-83   DOI   ScienceOn
28 Tanaka, N., Takaishi, Y., Shikishima, Y., Nakanishi, Y., Bastow, K., Lee, K.-H., Honda, G., Ito, M., Takeda, Y., Kodzhimatov, O. K. and Ashurmetov, O. (2004) Prenylated Benzophenones and Xanthones from Hypericum scabrum. J Nat. Prod. 67: 1870-1875   DOI   ScienceOn
29 Butterweck, V., Christoffel, V., Nahrstedt, A., Petereit, F., Spengler, B. and Winterhoff, H. (2003) Step by step removal of hyperforin and hypericin: Activity profile of different Hypericum preparations in behavioral models. Life Sci. 73: 627-639   DOI   ScienceOn
30 Yang, X.-D., Xu, L.-Z. and Yang, S.-L. (2001) Xanthones from the stems of Securidaca inappendiculata. Phytochemistry 58: 1245-1249   DOI   ScienceOn