Browse > Article

Isolation of a Cerebroside from Panax notoginseng  

Cho, Min-Jung (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Lee, So-Young (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Kim, Ju-Sun (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Lee, Je-Hyun (Department of Pharmaceutical Science, College of Pharmacy, Kyung Hee University)
Choi, Hwan-Soo (Korea Institute of Oriental Medicine)
Lee, Ho-Young (Korea Institute of Oriental Medicine)
Ha, Hye-Kyung (Korea Institute of Oriental Medicine)
Kim, Chung-Sook (Korea Institute of Oriental Medicine)
Kang, Sam-Sik (Natural Products Research Institute and College of Pharmacy, Seoul National University)
Publication Information
Korean Journal of Pharmacognosy / v.37, no.2, 2006 , pp. 81-84 More about this Journal
Abstract
A mixture of cerebrosid was purified from the roots of Panax notogiseng (Araliaceae) and characterized as 1-O-{\beta}-D-glucopyranosyl-(2S,3S,4R,8E)-2-[(2'R)-2‘-hydroxypalmitoylamino]-8-octadecene-1,3,4-triol (Aralia cerebroside) and its 8Z-isomer (1-O-{\beta}-D-glucopyranosyl-(2S,3S,4R,8E)-2-[(2'R)-2’-hydroxypalmitoylamino]-8-octadecene-1,3,4-triol, a major component of poke-weed cerebroside) by means of spectroscopic methods.
Keywords
Panax notoginseng; Araliaceae; cerebroside;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Falsone, G., Cateni, F., Visintin, G., Lucchini, V., Wagner, H., and Seligmann, O. (1994) Constituents of Euphorbiaceae 12. Comm. (1) Isolation and Structure Elucidation of Four New Cerebrosides from Euphorbia biglandulosa Desf, IL FARMACO, 49: 167-174
2 Falsone, G., Cateni, F., Baumgartner, M., Lucchini, V., Wagner, H., and Seligmann, O. (1994) Constituents of Euphorbiaceae 13.Comm. (1) Isolation and Structure Elucidation of Five Cerebrosides from Euphorbia characias L., Z. Naturforsch., 49B: 135-140
3 Sugiyama, S., Honda, M., and Komori, T. (1990) Stereochemistry of the Four Diastereomers of Phytosphingosine, Liebigs Ann. Chem., 1069-1078
4 Koga, J., Yamauchi, T., Shimura, M., Ogawa, N., Oshima, K., Umemura, K., Kikuchi, M., and Ogasawara N. (1998) Cerebrosides A and C, Sphingolipid Elicitors of Hypersensitive Cell Death and Phytoalexin Accumulation in Rice Plants, J. Biol. Chem., 273: 31985-31991   DOI   ScienceOn
5 Kang, S.S., Kim, J.S., Son, K.H., Kim, H.P., and Chang, H.W. (2001) Cyclooxygenase-2 Inhibitory Cerebrosides from Phytolaccae Radix, Chem. Pharm. Bull., 49: 321-323   DOI   ScienceOn
6 Kang, S.S., Kim, J.S., Xu, Y.N., and Kim, Y.H. (1999) Isolation of a New Cerebroside from the Root Bark of Aralia elata, J. Nat. Prod., 62: 1059-1060   DOI   ScienceOn
7 Ryu, J.-Y., Kim, J.S., and Kang, S.S. (2003) Cerebrosides from Longan Arillus, Arch. Pharrn. Res., 26: 138-142   DOI   ScienceOn
8 Kim, J.S., Byun, J.H., and Kang, S.S. (2001) Isolation of Soya-cerebrosideI from the Roots of Trichosanthes kirilowii, Nat. Prod. Sci., 7: 27-32
9 Komakine, N., Okasaka, M., Takaishi, Y., Kawazoe, K., Murakami, K., and Yamada, Y. (2006) New DammaraneType Saponin from Roots of Panax notoginseng, J. Nat. Med., 60: 135-137   DOI
10 Wang, C.-Z., McEntee, E., Wicks, S., Wu, J.-A., and Yuan, C.-S. (2006) Phytochemical and Analytical Studies of Panax notoginseng (Burk.) F.H. Chen, J. Nat. Med., 60: 97-105   DOI
11 Hori, T. and Sugita, M. (1993) Sphingolipids in Lower Animals, Prog. Lipid Res., 32: 25-45   DOI   ScienceOn
12 Couperus, P.A., Clague, A.D.H. and Van Dongen, J.P.C.M. (1976) $^{13}C$ Chemical Shifts of Some Model Olefins, Org. Magn. Reson., 8: 426-431   DOI
13 Liao, J., Tao, J., Lin, G. and Liu, D. (2005) Chemistry and Biology of Sphingolipids, Tetrahedron, 61: 4715-4733   DOI   ScienceOn
14 Fusetani, N., Yasumuro, K., Matsunaga, S., and Hirota, H. (1989) Haliclamines A and B, Cytotoxic Macrocyclic Alkaloids from a Sponge of the Genus Haliclona, Tetrahedron Lett., 30: 6891-6894   DOI   ScienceOn
15 Sugiyama, S., Honda, M., Higuchi, R., and Komori, T. (1991) Stereochemsitry of the Four Diastereomers of Ceramide and Ceramide Lactoside, Liebigs Ann. Chem., 349-356
16 Muralidhar, P., Radhika, P., Krishna, N., Venkata Rao, D., and Rao, C.B. (2003)Sphingolipids from Marine Organisms: A Review, Nat. Prod. Sci., 9: 117-142
17 배기환 (2003) 건강보감, 245, 교학사, 서울
18 Jung, J.H., Lee, C.-O., Kim, Y.C., and Kang, S.S. (1996) New Bioactive Cerebrosides from Arisaema amurense, J. Nat. Prod., 59: 319-322   DOI   ScienceOn