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Studies for Component Analysis and Biological Evaluation in Picrasma quassioides (D.Don) Benn. Extracts  

Jin, Ying-Shan (Division of Biotechnology, Kangwon National University)
Yin, Yu (Division of Biotechnology, Kangwon National University)
Shin, Tae-Heum (Gangwon Research Institute of Health and Environment)
Sa, Jae-Hoon (Gangwon Research Institute of Health and Environment)
Wang, Myeong-Hyeon (Division of Biotechnology, Kangwon National University)
Publication Information
Korean Journal of Pharmacognosy / v.37, no.1, 2006 , pp. 37-41 More about this Journal
Abstract
This study investigates the chemical components and biological activities in Picrasma quassioides (D.Don) Benn. extracts for the purpose of developing natural pharmaceutical products. The proximate components in Picrasma quassioides (D.Don) Benn. extracts were 81.56% of carbohydrate, 5.80% of crude fat, 7.75% of crude protein, and 2.07% of crude ash. Calcium was the most predominant mineral and followed phosphorus, potassium, sodium, and magnesium, in a decreasing order. The content of the unsaturated fatty acids, such as oleic acid, linoleic acid, and linolenic acid, was find to be higher than those of saturated fatty acids. Water and methanol extract exhibited antioxidative activity with $IC_{50}$ of $128{\mu}g/ml$ and $144{\mu}g/ml$, respectively, suggesting that the extracts are the major biological component in Picrasma quassioides (D.Don) Benn. extracts. The ${\alpha}-glucosidase$ inhibitory activity showed that methanol and water extract were the high inhibitory activity. Considering these results, water extracts of Picrasma quassioides (D/Don) Benn. showed the possibility that they can be used as a new material for natural pharmaceutical products.
Keywords
antioxidative activity; chemical components; Picrasma quassioides (D. Don) Benn.; biological activities; water extracts;
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1 Luyengi, L. Suh, N. and Fong, H. H. (1996) A lignan and four terpenoids from Brucea javanica that induce differentiation with cultured HL-60 promyelocytic leukemia cells. Phytochemistry. 43: 409-412   DOI   ScienceOn
2 Nayfeh, A. H. (1981) Introduction to perturbed techniques. 365-375. John Weiley & Sons, New York
3 Sung, I. S., Kim, M. J. and Cho, S. Y (1997) Effect of quercus acutissima carruthers extracts on the lipid metabolism. J. Korean Soc. Food Nutr. 26: 327-333   과학기술학회마을
4 Wong, S. F., Holliwell B., Richimond, R. and Skowroneck, W. R. (1981) The role of superoxide and hydroxyl radical in the degradation ofhyaluronic acid induced by metaljons and by ascorbic acid. J. Inorganic Biochem 14: 127-134   DOI   ScienceOn
5 Kang, M. H., Lee, J. H., Lee, J. S., Kim, J. H. and Chung, H. K. (2004) Effect of acorn supplementation on lipid profiles and antioxidant enzyme activities in high fat diet-induced obese rats. The Korean Nutr. Soc. 37: 169-175
6 A editorial committee (over 300 members) of the administration bureau oftraditional chinese medicine, chines materia medica (zhonghua benchao) (1998) Zhonghua bencao. 5: 13-17. Shanghai science & Technology Press, Shanghai
7 Lowry, O. H., Rodebrough, N. J., Farr, A. L. and Randall, R. J. (1951) Protein measurement with folin phenol reagent. J. Biol. Chem. 193: 265
8 Ohmoto, T., Nikaido, T., Koike, K., Kohda, K. and Sankawa, U. (1988) Inhibition of adenosine 3',5'-cyclic monophosphate phosphodiesterase by alkaloids. II. Chem Pharm Bull (Tokyo). 36: 4588-4592   DOI   ScienceOn
9 Han, J. S. and Han, Y. B. (1994) The effect of high fat diet and dietary fiber on lipid metabolism in rats. J. Korean Soc. Food Nutr. 23: 541-547
10 Hammerschmidt, P. A. and Pratt, D. E. (1977) Phenolic antioxidents of dried soybeans. J. Food Sci. 43: 556-561   DOI
11 Choi,J. H., Jang, J. G, Park, K. D., Park, M. H. and Oh, S. D. (1981) High performance liquid chromatographic determination of free sugars in ginseng and its products. Korean J. Food Sci. Technol. 13: 107-113
12 Lee, G. D., Kim, J. S., Bae, J. O. and Yoon, H. S. (1992) Antioxodative effectiveness ofwater extract and ether extract in Wormwood (Artemisia Montana Pampan). J. Korean Soc.Food Nutr. 21: 17-22
13 Imaida, K., Ishihara, Y, Nishio, O., Nakanishi, K. and Ito, N. (1983) Carcinogenicity ofbutylated hydroxy antisole in F344 rats. Toxicol Lett. 16: 259-269   DOI   ScienceOn
14 Murae, T., Tsuyuki, T., Ikeda, T., Nishihama, T. and Takahashi, T. (1971) Bitter Principles of Picrasma ailanthoides PLANCHON, Nigakilactones A, B, C, D, E, and F, Tetrahedron. 27: 1545-1555   DOI   ScienceOn
15 Fridovich, I. (1978) The biology of oxygen radicals, Science 201: 875   DOI
16 Metcalfe, L. D. and Schmitz, A. A. (1961) The rapid preparation of fatty acid estersfor gas chromatographic analysis. Anal. Chem. 33: 363-364   DOI
17 Frankel, E. N. (1996) Antioxidants in lipid foods and their on food quality. Food Chemistry. 57: 51-54   DOI   ScienceOn
18 Shim, T. H., Han, K. S., Lee, T. J., Cheong, E. H. and Lee, H. K. (1994) Composition of lipid and amino acid in Semisulcospira gottscheitissues, J. Food Hyg. Safety 9: 81-87   과학기술학회마을
19 Johnson, J. E, Walford, R., Hanna, D. and Miquel, J. (1986) Free radicals, aging and degenerative disease, 99. Alen R. Liss, N. Y
20 Kazuko, Y, Saori, S. and Shigenobu, A. (1995) Phenylpropanoids and other secondary metabolites from fresh fruits of Picrasma quassioides. Phytochemistry. 40: 253-256   DOI   ScienceOn
21 Corfrau, R. S., Kumar, V and Robbins, S. L. (1989) Robbins pathologic basis of disease, W. B. 1. Saunders, Philodelphia