Evaluation of a Schzandrin C Derivative DDB-mixed Preparation(DWP-04) on Acetaminophen Detoxification Enzyme System in the Animal Model
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Park, Hee-Juhn
(Division of Botanical Resources, Sangji university)
Lee, Myeong-Seon (Division of Botanical Resources, Sangji university) Chi, Sang-Cheol (College of Pharmacy, Sungkyunkwan University) Lee, Kyung-Tae (College of Pharmacy, Kyung-Hee University) Shin, Young-Ho (Dae Woo Pharmaceutical Ind. Co.) Choi, Jong-Won (College of Pharmacy, Kyungsung University) |
1 | Buege, J. A and Aust, S. D. (1978) Microsomal lipid peroxidation. Methods Enzymol. 52: 302-310 DOI |
2 | Griffith, O. W. (1980) Determination of glutathione and glutathione disulfide using glutathione reducetase and 2-vinylpyridine. Anal. Biochem. 106: 207-212 DOI PUBMED ScienceOn |
3 | Lowry, O. H., Rodebrough, N. J., Farr, A. L., and Randall, R.J. (1951) Protein measurement with the folin phenol reagent. J. Biol. Chem. 193: 265-275 |
4 | Bergmeyer, H. U., Scheibe, P., and Wahlifeld, A. W (1978) Optimization of methods for aspartate aminotransferase and alanine aminotransferase. Clin. Chem. 24: 58-73 |
5 | Paul, H. (1988) Perspectives on hydrogen peroxide and druginduced hemolytic anemia in glucose-6-phosphate dehydrogenase deficiency. Free Radical BioI. Med 5: 387-392 DOI ScienceOn |
6 | Sato, I.Y. (1966) Activation and inhibition of microsomal hydroxylation by ethyl isocyanide. Biochem.. Biophys.. Res.. Comm. 25: 80-86 DOI ScienceOn |
7 | Marinho, H. S., Marco, B., and Pinto. R. E.(1997) Glutathione metabolism in hepatomous liver of rats treated with diethylnitrosamine., Biochimica et Biophysica Acta. 1360: 157-168 DOI ScienceOn |
8 | Sangeeta, R., Neil, L. A., Misso, J. C., Lenzo, C. R., and Philip, J. T. (1999) Gamma y-glutamylcysteine synthetase activity in human lung epithelial (A549) cells: Factors influencing its measurement. Free Radical Biol. Med. 27: 1346-1356 DOI ScienceOn |
9 | Bidlack, W. R. and Lowry, G. L. (1982) Multiple drug metabolism: p-Nitroanisole reversal off acetone enhanced aniline hydroxylation. Biochem. Pharmacol. 31: 311-317 DOI ScienceOn |
10 | Dincer, Y, Alademir, Z., lkova, H., and Akcay, T. (2002) Susceptibility of glutatione and glutathione-related antioxidant activity to hydrogen peroxide in patients with type 2 diabetes: effect of glycemic control. Clin. Biochem. 35: 297-301 DOI ScienceOn |
11 | Prescott, L. F. and Wright, N. (1973) The effects of hepatic and renal damage on paracetamol metabolism and excretion following overdosage. A pharmacokinetic study. British J. Pharmacol. 49: 602-613 DOI ScienceOn |
12 | Thompson, T. N., Watkins, J. B., Gregus, Z., and Klaassen, C. D. (1982) Effect of microsomal enzyme inducers on the soluble enzymes of hepatic phase II biotransformation. Toxicol. Applied Pharmacol. 66: 400-408 DOI ScienceOn |
13 | Mize, C. E. and Langdon, R. G (1962) Hepatic glutathione reductase: I. Purification and general kinetic properties. J. BioI. Chem. 237: 1589-1595 |
14 | Purnford, N. R, Haimes, N. C., Martin, B. M., Cook, R. J., Wagner, C., and Hinson, J. A (1997) Covalent binding of acetaminophen to N-10-formyltetrahydrofolate hydrogenase in mice. J. Pharmaco. Exp. Ther. 280: 501-505 |
15 | Lim, H. K., Kim, H. S., and Choi, J. W. (2000) Therapeutic effects of bergenin and actylbergenin on galactosamineinduced hepatotoxicity in rats. Kor. J. Pharmacogn 31: 351-356 |
16 | Wendel, A. and Feuerstein, S. (1981) Drug-induced lipid peroxidation in mice-I. Modulation by monooxygenase activity, glutathione and selenium status. Biochem. Pharmacol. 30: 2513-2520 DOI PUBMED ScienceOn |
17 |
Serviddio, G, Vendemiale, G, Altomare, E., Poli, G, Pallardo, F., Vina, J., and Sastre, J. (2003) Ursodeoxycholic acid protects liver mitochondria against oxidative stress in secondary biliary cirrhosis via up-regulation of gamma |
18 | Dodds, M. G. and Foard, R. D. (1970) Enhancement by potent diuretics of renal tubular necrosis induced by cephaloridine. Br. J. Pharmacol. 40: 227-236 DOI ScienceOn |
19 | Prochaska, H. J. and Santamaria, A. B. (1988) Direct measurement of NAD(p)H:puinone reductase from cells cultured in microtiter wells: a screening assay for anticarcinogenic enzyme inducers. Anal. Biochem. 169: 328-336 DOI ScienceOn |
20 | Iyer, K. R. and Sinz, M. W. (1999) Characterization of Phase I and Phase II hepatic drug metabolism activities in a panel of human liver preparations. Chemico-Biological Interactions. 118: 151-169 DOI ScienceOn |
21 | Salvi, A, Carrupt, P. A, Tillement, J. P., and Bernard Testa, B. (2001) Structural damage to proteins caused by free radicals: asessment, protection by antioxidants, and influence of protein binding. Biochem. Pharmacol. 61: 1237-1243 DOI PUBMED ScienceOn |
22 | Imai, Y, Ito, A, and Sato, R (1966) Evidence for biochemically different types of vesicles in the hepatic microsomal fraction. J .Biochem.. 60: 417-441 DOI |
23 | Michaell, J. R., Jollow, D. J., Potter, W. Z., Gillette, J. R, and Brodie, B.B. (1973) Acetaminophen-induced hepatic necrosis. IV. Protective role of gluatathione. J. Pharmacol. Exp. Ther. 187: 211-217 |
24 | Hajos, A. K. D. and Winston, G. W. (1992) Role of cytosolic NAD(P)H-quinone oxidoreductase and alcohol dehydrogenase in the reduction of p-nitrosophenol following chronic ethanol ingestion. Arch. Biochem .Biophy. 295: 223-229 DOI ScienceOn |
25 | Slattery, J. and Levy, G (1979) Acetaminophen kinetics in acutely poisoned patients. Clin. Pharmacol. Ther. 25: 184185 |
26 | Nash, T. (1953) The colorimetric estimation offormaldehyde by means of the hentisch reaction. J. Bioi. Chem. 55: 416-423 |
27 | Mitchell. J. R. Jollow. D. J.. Potter. W. Z.. Davis. D. C.. Gillette, J. R., and Brodie, B. B. (1973) Acetaminopheninduced hepatic necrosis. I. Role of drug metabolism. J. Pharmacol. Exp. Ther. 187: 185-194 |
28 | Meister, A. and Anderson, M. E. (1983) Glutathione. Annu. Rev. Biochem. 52: 711-760 DOI ScienceOn |
29 | Lee, J. H., Chi, S. C., Kim, S. H., Shin, Y. H.,Park, H. J., and Choi, J. W (2005) Preventive effect of a Schzandrin C derivative DDB-mixted preparation against hepatotoxicity induced by Carbon Tetrachloride. Kor. J. Pharmacogn. 36: in press |
30 | Habig, W. H., Pabist,M. J., and Jakoby, W B. (1974) Glutathion S-trasferase: Thefrrst enzymatic step in mercapturic acid formation. J. Bioi. Chem. 249: 7130-7139 |
31 | Herod, I. A. and Gangolli, S. D. (1980) The effect of treatment with some phase II substrates on hepatic xenobiotic metabolism and the urinary excretion of metabolites of the glucuronic acid pathway in the rat. Toxicol. Applied Pharmacol. 52: 371-378 DOI ScienceOn |
32 | Meredith, T. J. and Vale, J.A .(1986) Non-narcotic analgesics problems of overdosage. Drugs. 32: 177-205 DOI PUBMED |
33 | Halliwell, B. (1978) Biochemical mechanism accounting for ghe toxic action of oxygen on living organisms: The key role of superoxide dismutase. Cell Biol. Int.. Rep. 2: 113-128 DOI PUBMED ScienceOn |
34 | Webster, P. A, Roberts, D. W, Benson. R W, and Keams, G.L.(1996) Acetaminophen toxicity in children: diagnostic confirmation using specific antigen biomaker. J. Clin. Phamacol. 36: 397-402 |
35 | Mark, A. B., Anatoly, I. D., and Leonid, F. L. (1988) Lipid peroxidation as a possible cause of cataract. Mechanisms of Ageing and Development, 44: 69-89 DOI ScienceOn |
36 | Nicolas, G, Marcos, M., Juan, A., Carlos, S., Antonio, P., and Jose, R. (2004) Relationship among standard semen parameters, glutathione peroxidase/glutathione reductase activity, and mRNA expression and reduced glutathione content in ejaculated spermatozoa from fertile and infertile men. Fertility and Sterility, 82: 1059-1066 DOI ScienceOn |
37 | Awasthi, Y. C., Beutler, E., and Srivastava, S. K.(1975) Purification and properties ofhuman erythrocyte glutathione peroxidase. J .Biol. Chem. 250: 5144-5149 |
38 | Ahokas, J. T., Davies, C., Ravenscroft, P. J., and Emmerxon, B. T. (1984) Inhibition of souble glutathione S-transferase by diuretic drugs. Biochem.. Pharmacol. 33: 1929-1932 DOI ScienceOn |
39 | Cohen, S. D. and Khairallah, E. A. (1997) Selective protein covalent binding and acetaminophen-induced hepatotoxicity. Drug Metabolism Review. 29: 59-77 DOI ScienceOn |
40 | Ray, S. D., Mumaw, V. R, Raje, R. R, and Fariss, M. W (1996) Protection of AAP-induced hepatocellular apoptosis and necrosis by cholesteryl hemisuccinate pretreatment. J. Pharmacol. Exp. Ther. 279: 1470-1483 |
41 | Meister, A. and Richman, P.G. (1975) Regulation of glutamyl- cysteine synthesis by nonallosteric feedback inhibition by glutathione. J. Biol. Chem. 250: 1422-1429 |
42 | Meredith, T. J. and Vale, J. A (1984) Epidermiology of analgesic overdose in England and Wales. Human Toxicol. 3: 61S-74S DOI |
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