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Inhibitors of Melanogenesis from Atractylodes rhizomes  

Jung, Min-Hwan (Corporate R&D of LG Chem./Research Park(E))
Moon, Chul-Soon (Corporate R&D of LG Chem./Research Park(E))
Lim, Young-Hee (Corporate R&D of LG Chem./Research Park(E))
Kang, Sang-Jin (C.I. Center of LG Household & Health Care Ltd.)
Cho, Wan-Goo (C.I. Center of LG Household & Health Care Ltd.)
Kim, Cheong-Taek (C.I. Center of LG Household & Health Care Ltd.)
Publication Information
Korean Journal of Pharmacognosy / v.36, no.1, 2005 , pp. 60-63 More about this Journal
Abstract
One sesquiterpenoid was isolated from the methanol extract of Atractylodes rhizomes which has been used as traditional medicine for diuresis and the compound was established as selina-4(14),7(11)-dien-8-one by the spectroscopic methods. The compound$(IC_{50}<10\;ppm)$ has inhibitory effects on melanogenesis in B16 mouse melanoma.
Keywords
Sesquiterpenoid; Atractylodes rhizomes; selina-4(14),7(11)-dien-8-one; B16 mouse melanoma; melanogenesis;
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