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Glutathione S-transferase Activity and Hyaluronidase Inhibitory Effect of Medicinal Plants  

Lee, Eun-Hee (Department of Bio-Industry and Technology, Sangji University)
Cho, Jae-Yong (Department of Bio-Industry and Technology, Sangji University)
Cha, Bae-Cheon (Department of Bio-Industry and Technology, Sangji University)
Publication Information
Korean Journal of Pharmacognosy / v.35, no.3, 2004 , pp. 184-188 More about this Journal
Abstract
This study was carried out to evaluate glutathione S-transferase (GST) activity and hyaluronidase inhibitory effect of medicinal plants. The EtOH extracts of 20 species plants were tested. As the result, Acorus gramineus and Pueraria lobata exhibited GST activity. On the continuous experiment, the n-BuOH fraction of Acorus gramineus and the $H_2O$ fraction of Pueraria lobata showed the elevation of GST activity. On the experiment of hyaluronidase inhibitory effect, Acorus gramineus exhibited a potent inhibitory activity. These results suggest that the extract of Acorus gramineus can be applicable for the development of a new anti-inflammatory agent.
Keywords
Glutathione S-transferase; Hyaluronidase inhibitory effect; Medicinal plants; Pueraria lobata; Acorus gramineus;
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