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Quantitative Analysis of Psoralen and Angelicin in the Psoraleae Semen and Processed Psoraleae Semen  

Lee, Hye-Won (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Chun, Jin-Mi (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Lee, A-Yeong (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Ko, Byoung-Seob (Department of Herbal Research, Korea Institute of Oriental Medicine)
Kim, Ho-Kyoung (Department of Quality Control of Herbal Medicine, Korea Institute of Oriental Medicine)
Publication Information
Korean Journal of Pharmacognosy / v.35, no.3, 2004 , pp. 179-183 More about this Journal
Abstract
Psoralen is used in the treatment of vitiligo and angelicin(isopsoralen) is a photosensitizing agent. A reversed-phase high performance chromatographic method was developed to determine the contents of psoralen and angelicin from Psoraleae Semen and processed Psoraleae Semen. The contents of psoralen and angelicin from Psoraleae Semen showed 0.39% and 0.34% respectively. Processing Psoraleae Semen showed that increased the contents of psoralen (0.52%) and angelicin (0.50%).
Keywords
Psoraleae Semen; Processed Psoraleae Semen; Psoralen; Angelicin; HPLC;
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