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Phenolic Compounds from Seeds of Astragalus sinicus and Its Antioxidative Activities  

Yeom, Seung-Hwan (College of Pharmacy, Chung-Ang University)
Kim, Min-Kee (College of Pharmacy, Chung-Ang University)
Kim, Hyun-Jung (College of Pharmacy, Chung-Ang University)
Shim, Jae-Geul (College of Pharmacy, Chung-Ang University)
Lee, Jae-Hee (College of Pharmacy, Chung-Ang University)
Lee, Min-Won (College of Pharmacy, Chung-Ang University)
Publication Information
Korean Journal of Pharmacognosy / v.34, no.4, 2003 , pp. 344-351 More about this Journal
Abstract
Phytochemical examination of seeds of Astragalus sinicus has led to the isolation and characterization of kaempferol $3-O-{\beta}-D-apiofuranosyl-(1{\rightarrow}2)-{\alpha}-L-rhamnopyranosyl-(1{\rightarrow}6)-{\beta}-D-glucopyranoside$ (1), quercetin $3-O-{\beta}-D-xylopyranosyl-(1{\rightarrow}2)-{\beta}-D-glucopyranoside$ (2), ampelopsin (3), ampelopsin $3 (4), ampelopsin $3 (5), myricetin (6), myricetin $3 (7), myricetin $3 (8). Antioxidative activity of these compounds was determined by measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals. Flavanonols(3,4, and 5) showed potent antioxidative activity.
Keywords
Astragalus sinicus; Flavonoid; Antioxidative activities;
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