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In Vitro Free Radical Scavenging and Hepatoprotective Activities of Taraxacum mongolicum  

Baek, Hum-Young (Jungwoo Pharmaceutical Co., Ltd.)
Publication Information
Korean Journal of Pharmacognosy / v.34, no.4, 2003 , pp. 324-326 More about this Journal
Abstract
The methanol (MeOH) extract and ist fractions of Taraxacum mongolicum (Compositae) were examined for their scavenging effects on 1,1-diphenyl-2- phenylhydrazyl (DPPH) and superoxide radicals, and hepatoprotective effects on tacrine-induced cytotoxicity in human hepatoma cell line, Hep G2 cells. Both methylene chloride $(CH_2Cl_2)$ and butanol (n-BuOH) soluble fractions of the MeOH extract showed the free radicals scavenging and hepatoprotective effects. From these results, it is suggested that hepatoprotective effect of these fractions partly relies on their free radical scavenging activity.
Keywords
Taraxacum mongolicum; Compositae; 1,1-diphenyl-2-phenylhydrazyl; superoxide radical; hepatoprotective; Hep G2 cells;
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