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Comparative Activity of Medicinal Herbs Between Hollow Fiber Assay and Xenographic Animal Assay  

Cho, Choa-Hyung (Department of Food Engineering Iksan National College)
Yoon, Won-Ho (Department of Food Science & Technology Seoil College)
Lee, Keyong-Ho (Kolon Central Research Park)
Publication Information
Korean Journal of Pharmacognosy / v.34, no.4, 2003 , pp. 288-292 More about this Journal
Abstract
We compared the antitumor activity between hollow fiber assay and xenographic animal assay on thirty herbal plants. It is evaluated that the antitumor activity of above 30% is regarded as 'positive response', and its of below 30% is regarded as 'negative response'. The two herbal plants extracts (Ulmus davidiana Hedyotis diffusa) among thirty herbal plants show to be positive in xenographic animal assay and they were also correctly identified as positive by the hollow fiber assay. The correlation of the hollow fiber assay data with xenographic animal assay would suggest that hollow fiber assay presents a potentially unique tool to develop the herbal medicine for cancer.
Keywords
Hollow fiber; xenographic; antitumor; correlation; herbs; Ulmus davidiana; Hedyotis diffusa;
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