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http://dx.doi.org/10.20408/jti.2018.048

Recurrence of Minimal Change Disease Following a Motor Vehicle Trauma: An Atypical Cause and Review of Literature  

Depa, Jayaramakrishna (Department of Nephrology, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai)
Coritsidis, George (Department of Nephrology, Elmhurst Hospital Center, Icahn School of Medicine at Mount Sinai)
Publication Information
Journal of Trauma and Injury / v.32, no.2, 2019 , pp. 111-114 More about this Journal
Abstract
Minimal change disease (MCD) in children has a favorable long-term prognosis, and development of end-stage renal disease is very uncommon; less than 5%. In the first case of its kind, we report a 21-year-old female with a history of MCD at the age of 6, who had late relapse subsequent to a motorcycle accident resulting in a de-gloving skin injury and intensive care unit admission. MCD was confirmed by normal light microscopy, podocyte effacement on electron microscopy and absence of any deposits on immunofluorescence 3 weeks after the incident due to critical illness. It is postulated that the skin injury is what caused the relapse of MCD.
Keywords
Minimal change disease; Skin injury; Recurrence; Nephrology; End-stage renal disease;
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