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Development of Biomimetic Scaffold for Tissue Engineering  

Park, Su-A (Nano-Mechanical Systems Research Division, Korea Institute of Machinery & Materials (KIMM))
Lee, Jun-Hee (Nano-Mechanical Systems Research Division, Korea Institute of Machinery & Materials (KIMM))
Kim, Wan-Doo (Nano-Mechanical Systems Research Division, Korea Institute of Machinery & Materials (KIMM))
Publication Information
Elastomers and Composites / v.44, no.2, 2009 , pp. 106-111 More about this Journal
Abstract
Tissue engineering is a research field for artificial substitutes to improve or replace biological functions. Scaffolds play a important role in tissue engineering. Scaffold porosity and pore size provide adequate space, nutrient transportation and cell penetration throughout the scaffold structure. Scaffold structure is directly related to fabrication methods. This review will introduce the current technique of 3D scaffold fabrication for tissue engineering. The conventional technique for scaffold fabrication includes salt leaching, gas foaming, fiber bonding, phase seperation, melt moulding, and freeze drying. These conventional scaffold fabrication has the limitations of cell penetration and interconnectivity. In this paper, we will present the solid freeform fabrication (SFF) such as stereolithography (SLA), selective laser sintering (SLS), and fused deposition modeling (FDM), and 3D printing (3DP).
Keywords
tissue engineering; scaffold; solid freeform fabrication;
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