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http://dx.doi.org/10.9724/kfcs.2013.29.3.241

Comparison of Antioxidant and Anti-proliferative Activities of Perilla (Perilla frutescens Britton) and Sesame (Seasamum indicum L.) leaf extracts  

Kwak, Youngeun (Department of Food and Nutrition, Chungbuk National University)
Ki, Seoha (Department of Food and Nutrition, Chungbuk National University)
Noh, Eun Kyoung (Department of Food and Nutrition, Chungbuk National University)
Shin, Ha Neul (Department of Food and Nutrition, Chungbuk National University)
Han, Young-Ju (Department of Food and Nutrition, Chungbuk National University)
Lee, Yuna (Department of Food and Nutrition, Chungbuk National University)
Ju, Jihyeung (Department of Food and Nutrition, Chungbuk National University)
Publication Information
Korean journal of food and cookery science / v.29, no.3, 2013 , pp. 241-248 More about this Journal
Abstract
This study was to compare the antioxidant and anti-proliferative activities of perilla (Perilla frutescens Britton) and sesame (Seasamum indicum L.) leaf extracts. The total polyphenol levels of sesame leaf ($634.7{\pm}1.2$ mg gallic acid equivalent/100 g dried leaf) were higher than those of perilla leaf ($408.7{\pm}4.6$ mg gallic acid equivalent/100 g dried leaf; p<0.001). The total flavonoid levels of sesame leaf ($166.7{\pm}17.3$ mg quercetin equivalent/100 g dried leaf) were also higher than those of perilla leaf ($108.2{\pm}3.7$ mg quercetin equivalent/100 g dried leaf; p<0.05). ABTS radical- and DPPH radical-scavenging activities of sesame leaf extracts (78.9% and 18.2%, respectively) were higher than those of perilla leaf extracts (46.0% and 9.0%, respectively; p<0.01). Both perilla and sesame leaf extracts significantly inhibited the growth of HCT116 human colon cancer cells. However, the inhibitory activities of sesame leaf extracts were more pronounced than those of perilla leaf extracts (p<0.001). These results indicate that sesame leaf extracts have higher antioxidant and anti-proliferative activities than perilla leaf extracts. More studies are needed in order to enhance the sensory value of sesame leaf and to develop sesame leaf as health/functional food ingredients.
Keywords
Sesame leaf; perilla leaf; antioxidant activity; anti-proliferative activity; HCT116 colon cancer cell;
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Times Cited By KSCI : 7  (Citation Analysis)
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