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Sex-Hormone Replacement Effect of Silkworm Pupa and Mixture with Herbs  

Yang Ji-Won (Department of Food Nutrition, Kyung Hee University)
Choi Eun-Mi (Department of Food Nutrition, Kyung Hee University)
Kwon Mu-Gil (Kunwha Pharmaceutical Co., Ltd.)
Koo Sung-Ja (Department of Food Nutrition, Kyung Hee University)
Publication Information
Korean journal of food and cookery science / v.21, no.6, 2005 , pp. 769-775 More about this Journal
Abstract
In this study we isolate substances to serve as dietary resources in order to replace the female hormone. Silkworm (Bombyx mori) is one of the most attractive hosts for large-scale production of eukaryotic proteins which have been proven safe as a dietary resource. We report on the estrogenicity of a mixture of silkworm pupa and herbs (Ginseng,Ulkeum, and Hasuo) using the immature rat uterotrophic assay in vivo. Silkworm pupa aqueousextract (KW) and silkworm oil extract (KO) induced effects on the immature rat uterotrophic assay. KO showed neither positive uterotrophic response nor inhibition on E2 induced effect, while KW and MK (mixture of KW and herbs) showed both of the effects. It is concluded that ethanol extracts from silkworm might be a good, therapeutic, natural product for hormone-deficient diseases.
Keywords
Silkworm pupa; herb; immature rat uterotrophic assay;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
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