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http://dx.doi.org/10.15230/SCSK.2022.48.3.275

Identification of Anti-oxidant, Anti-aging, and Whitening Effects of Diospyros kaki Extracts  

Hong, Chang-Eui (College of Pharmacy, Sunchon National University)
Lyu, Su-Yun (College of Pharmacy and Research Institute of Life and Pharmaceutical Sciences, Sunchon National University)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.48, no.3, 2022 , pp. 275-285 More about this Journal
Abstract
In this study, we prepared two extracts using 1,3-butylene glycol (DBG) and ethanol (DET), with Diospyros kaki and determined the anti-oxidant, anti-aging, and whitening effects in vitro. Anti-oxidant activity was measured by DPPH and superoxide dismutase (SOD) method, and as a result, both DBG and DET extracts confirmed their anti-oxidant properties by exhibiting significant DPPH scavenging and SOD-like activities. For anti-aging activity, we measured elastase and hyaluronidase inhibition, and the inhibition of MMP-1 expression. Both DBG and DET significantly inhibited elastase and hyaluronidase activities dose-dependently, and MMP-1 expression was also reduced in both extracts. We also measured the whitening effects with tyrosinase activity and melanin production, but only DBG showed a decrease in tyrosinase. In summary, D. kaki extract has strong antioxidant, anti-aging, and whitening functions, and it is believed that it can be used as a cosmetic material in the future.
Keywords
Diospyros kaki; anti-oxidant; anti-aging; whitening;
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