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http://dx.doi.org/10.15230/SCSK.2022.48.1.65

Anti-pigmentation Effects of Panax vietnamensis Extracts via Tyrosinase Expression  

Kim, Young Joo (Osan university, Department of Beauty & Cosmetics, Osan University)
Cha, Hwa Jun (Osan university, Department of Beauty & Cosmetics, Osan University)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.48, no.1, 2022 , pp. 65-70 More about this Journal
Abstract
In this study, the anti-pigmentation efficacy of Panax vietnamensis (P. vietnamensis), a ginseng native to Vietnam, was confirmed. Melanin synthesis was repressed by ethanolic extracts of P. vietnamensis in B16F10 cells, melanocytes originated from mouse. At 250 ㎍/mL ethanolic extracts of P. vietnamensis, melanin contents were repressed by 64.04% compared to the control group. In addition, ethanolic extracts of P. vietnamensis downregulated tyrosinase activity and expression to 53.34% and 59.39%, respectively. As shown our result, ethanolic extracts of P. vietnamensis blocks α-MSH-mediated melanogenesis and is valuable whitening ingredients in cosmetics.
Keywords
Panax vietnamensis; melanin; pigmentation; tyrosinase;
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Times Cited By KSCI : 6  (Citation Analysis)
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