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http://dx.doi.org/10.15230/SCSK.2021.47.1.23

A Study on the Activities of Five Natural Plant Essential Oils on Atopic Dermatitis  

Jeong, Jeong-Hwa (Dongje Medical)
Nguyen, Thao Kim Nu (Vietnam Type Culture Collection, Institute of Microbiology and Biotechnology, Vietnam National University)
Choi, Min-Jin (Department of Physiology, College of Korean Medicine, Dongguk University)
Nguyen, Ly Thi Huong (Department of Physiology, College of Korean Medicine, Dongguk University)
Shin, Heung-Mook (Department of Physiology, College of Korean Medicine, Dongguk University)
Lee, Byung-Wook (Department of Medical Classics and History, College of Korean Medicine, Dongguk University)
Yang, In-Jun (Department of Physiology, College of Korean Medicine, Dongguk University)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.47, no.1, 2021 , pp. 23-30 More about this Journal
Abstract
This study is an experiment to evaluate the anti-atopy efficacy of five kinds of natural plant essential oils; Artemisia annua L. (AA), Citrus junos Sieb. ex TANAKA (CJ), Chrysanthemum boreale Makino (CB), Pinus koraiensis (PK), and Pinus densiflora for. erecta (PD). Through Agar diffusion test, five species of native plant essential oils were treated in a total of four strains, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Candida albicans. In order to invest the anti-inflammatory effect, five kinds of natural plant essential oils were treated in HaCaT cells-induced by TNF-α and IFN-γ (TI). AA, CJ, CB, PK and PD showed antibacterial effects on Candida albicans at a concentration of 10 mg/mL. We also found that the thymus and activation-regulated chemokine (TARC) expression was suppressed in 0.1 ㎍/mL of PK, 1 ㎍/mL of AA, CB, and PK. macrophage-derived chemokine (MDC) expression was suppressed in 1 ㎍/mL of AA and PK. IL-6 expression was suppressed in 0.1, 1 ㎍/mL of AA, PK in HaCaT cells. Hence it suggests that AA, CB, and PK have the anti-inflammatory effects, and it could contribute to atopic dermatitis relief by reducing the infiltration of immune cells to inflamed area.
Keywords
native plant; essential oil; atopic dermatitis; anti-microbial; anti-inflammation;
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1 U. Wollina, W. Kunkel, L. Bulling, C. Funfstuck, B. Knoll, I. Vennewald, and U. C. Hipler, Candida albicans-induced inflammatory response in human keratinocytes, Mycoses, 47(5-6), 193 (2004).   DOI
2 J. B. Travers, A. Kozman, N. Mousdicas, C. Saha, M. Landis, M. Al-Hassani, W. Yao, Y. Yao, A.-M. Hyatt, and M. P. Sheehan, Infected atopic dermatitis lesions contain pharmacologic amounts of lipoteichoic acid, J/Allergy Clin. Immunol., 125(1), 146 (2010).   DOI
3 A. K. Syed, T. J. Reed, K. L. C lark, B. R. Boles, and J. M. Kahlenberg, Staphlyococcus aureus phenol-soluble modulins stimulate the release of proinflammatory cytokines from keratinocytes and are required for induction of skin inflammation, Infect. Immun., 83(9), 3428 (2015).   DOI
4 N. Dargahi, J. Johnson, O. Donkor, T. Vasiljevic, and V. Apostolopoulos, Immunomodulatory effects of probiotics: C an they be used to treat allergies and autoimmune diseases?, Maturitas, 119, 25 (2019).   DOI
5 A. Vijayaraghava and V. Doreswamy, Exercise and the cytokines-interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α): A review, Ann. Med. Physiol., DOI, (2017).
6 K. S. Li, Itch in atopic dermatitis: from pathogenesis to treatment, Allergy Asthma Respir. Dis., 2(1), 8 (2014).   DOI
7 Y. Ha, W. H. Lee, J. W. Jeong, M. R. Park, J. Y. Ko, O. W. Kwon, J. S. Lee, and Y. J. Kim, Pyropia yezoensis Extract suppresses IFN-Gamma-and TNF-alpha- induced proinflammatory chemokine production in HaCaT cells via the down-regulation of NF-κB, Nutrients, 12(5), 1238 (2020).   DOI
8 E. J. Jeong and J. D. Kim, A study on the utilization and effect of essential oil, J. Korean Soc. Cosmet. Cosmetol., 1, 93 (2011).
9 S. Y. Eun, J. J. Yoon, H. Y. Kim, Y. M. Ahn, B. H. Han, M. H. Hong, C. O. Son, S. W. Na, Y. J. Lee, D. G. Kang, and H. S. Lee, Protective effects of Chijabaegpitang on atopic dermatitis in TNF-α/IFNγ-induced HaCaT cells., J. Physiol. & Pathol. Korean Med., 32(4), 226 (2018).   DOI
10 T. W. Song, B. C. Kwon, S. Y. Choi, Y. H. Shin, K. E. Lee, H. S. Yang, K. W. Kim, E. S. Kim, M. H. Sohn, and K. E. Kim, Increased serum thymus and activation-regulated chemokine (TARC) levels in children with atopic dermatitis, Pediatr. Allergy Respir. Dis., 15(3), 250 (2005).
11 R. S. Young and K. K. Ha, Effects of aroma massage on pruritus, skin pH, skin hydration and sleep in elders in long-term care hospitals, J. Korean Acad. Nurs., 43(6), 726 (2013).   DOI
12 S. J. Park, J. S. Lee, K. M. Ahn, and S. J. Chung, The comparison of growth and nutrient intakes in children with and without atopic dermatitis, Korean J. Community Nutr., 17(3), 271 (2012).   DOI
13 C. Y. Han, J. G. Park, D. W. Kang, S. Y. Park, B. H. Kim, Y. B. Kim, and K. S. Kim, Analysis of Case Studies of Treating Atopic Dermatitis, J. Korean Med. Ophthalmol. Otolaryngol. Dermatol., 32(3), 151 (2019).   DOI
14 Y. S. Yoo and M. S. Na, Inhibitory effect on acne using anti-bacteria of lavender essential oil in adolescents, Kor. J. Aesthet. Cosmetol., 8(4), (2010).
15 S. D. Cox, C. M. Mann, J. L. Markham, H. C. Bell, J. E. Gustafson, J. R. Warmington, and S. G. Wyllie, The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil), J. Appl. Microbiol., 88(1), 170 (2000).   DOI
16 G. S. Lim, R. Kim, H. Cho, Y. S. Moon, and C. N. Choi, Comparison of volatile compounds of Chamaecyparis obtusa essential oil and its application on the improvement of atopic dermatitis, KSBB J., 28(2), 115 (2013).   DOI
17 E. V. Ramos Campos, P. L. F. Proenca, L. Doretto-Silva, V. Andrade-Oliveira, L. F. Fraceto, and D. R. de Araujo, Trends in nanoformulations for atopic dermatitis treatment, Expert Opin. Drug Deliv., 17(11), 1615 (2020).   DOI
18 D. Y. Jang and J. C. Yang, A Study on the evaluation of antimicrobial activity of extracts from Rhus javanica L fruit, J. Korean Appl. Sci. Technol., 37(1), 145 (2020).
19 E. Morita, M. Hide, Y. Yoneya, M. Kannbe, A. Tanaka, and S. Yamamoto, An assessment of the role of Candida albicans antigen in atopic dermatitis, J. Dermatol., 26(5), 282 (1999).   DOI
20 A. R. Bilia, C. Guccione, B. Isacchi, C. Righeschi, F. Firenzuoli, and M. C. Bergonzi, Essential oils loaded in nanosystems: a developing strategy for a successful therapeutic approach, Evid. Based Complement. Alternat. Med., 2014, (2014).
21 A. F. Bento, R. Marcon, R. C. Dutra, R. F. Claudino, M. C ola, D. F. P. Leite, and J. B. C alixto, β-Caryophyllene inhibits dextran sulfate sodium-induced colitis in mice through CB2 receptor activation and PPARγ pathway, Am. J. Pathol., 178(3), 1153 (2011).   DOI
22 C. I. Park, A study on the skin protection effects of Cypress essential oil on the DNCB-induced atopic dermatitis in NC/Nga mice, Korea J. Herbol., 32(3), 37 (2017).   DOI
23 E. C. Choi, Ph. D. Dissertation, Hoseo Univ., Chungnam, Korea (2018).
24 N. Rani, P. Kumar, R. Singh, and A. Sharma, Molecular docking evaluation of Imidazole analogues as potent Candida albicans 14α-Demethylase inhibitors, Curr. Comput. Aided Drug Des., 11(1), 8 (2015).   DOI
25 R.-Y. Lai, S. Huang, M. K. Fenwick, A. Hazra, Y. Zhang, K. Rajashankar, B. Philmus, C . Kinsland, J. M. Sanders, and S. E. Ealick, Thiamin pyrimidine biosynthesis in Candida albicans: a remarkable reaction between histidine and pyridoxal phosphate, J. Am. Chem. Soc., 134(22), 9157 (2012).   DOI
26 B. T. P. Thuy, T. T. A. My, N. T. T. Hai, H. T. P. Loan, N. T. T. Thuy, N. T. Triet, T. T. Van Anh, N. T. X. Dieu, P. T. Quy, and N. Van Trung, Screening for Streptococcus pyogenes antibacterial and Candida albicans antifungal bioactivities of organic compounds in natural essential oils of Piper betle L., Cleistocalyx operculatus L. and Ageratum conyzoides L., Chem. Pap., 75, 1507 (2020).
27 R. Y. Kang, B. K. Park, S. B. Gim, H. J. Choi, and D. H. Kim, The effects of HYT on various immunological factors related to pathogenesis of allergic dermatitis in NC/Nga mice induced by Biostir AD, J. Haehwa Med., 18(2), 47 (2009).
28 F. Juteau, V. Masotti, J. M. Bessiere, M. Dherbomez, and J. Viano, Antibacterial and antioxidant activities of Artemisia annua essential oil, Fitoterapia, 73(6), 532 (2002).   DOI
29 J. M. Lee, S. Han, S. L. Lee, J. Y. Park, H. M. Kim, and S. H. P. Lee, GC/MS analysis of volatile constituents from Zizyphus jujuba var. inermis, Zanthoxylum piperitum, Gardenia jasminoides for. grandiflora, and Pinus koraiensis, Korean J. Hortic. Sci. Technol., 26(3), 338 (2008).
30 K. J. Kim, Y. H. Kim, H. H. Yu, S. I. Jeong, J. D. Cha, B. S. Kil, and Y. O. You, Antibacterial activity and chemical composition of essential oil of Chrysanthemum boreale, Planta Med., 69(03), 274 (2003).   DOI
31 D. S. Kim, H. J. Lee, Y. D. Jeon, Y. H. Han, J. Y. Kee, H. J. Kim, H. J. Shin, J. W. Kang, B. S. Lee, and S. H. Kim, Alpha-pinene exhibits anti-inflammatory activity through the suppression of MAPKs and the NF-κB pathway in mouse peritoneal macrophages, Am. J. Chin. Med., 43(04), 731 (2015).   DOI
32 M. K. Lee, K. Y. Park, T. W. Jin, W. J. Oh, and S. J. Seo, Distribution of skin and oral microorganisms in atopic dermatitis, Korean J. Dermatol., 54(1), 1 (2016).