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http://dx.doi.org/10.15230/SCSK.2020.46.4.339

Antioxidant, Antimicrobial and Anti-inflammatory Effect of Boehmeria nivea var. nipononivea Extracts  

Jung, Gi Soo (Jeju Biological Resource Co., Ltd)
Lee, Sun Hee (Jeju Biological Resource Co., Ltd)
Yang, Soo-Kyung (Jeju Biological Resource Co., Ltd)
Moon, Sung Pil (Jeju Biological Resource Co., Ltd)
Song, Gwanpil (Jeju Biological Resource Co., Ltd)
Kim, Ji Young (Jeju Biological Resource Co., Ltd)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.46, no.4, 2020 , pp. 339-348 More about this Journal
Abstract
The purpose of this study was to investigate the possible use of the Boehmeria nivea var. nipononivea extract and fractions for the development of natural cosmetic ingredients. The leaves of B. nivea var. nipononivea, extracted by 70% ethanol, were sequentially fractionated with n-hexane, dichloromethane, ethylacetate, and n-butanol. As a result of DPPH and ABTS test, ethyl acetate fractionation was shown to be excellent in radical scavenging activity. For the antimicrobial activities against Staphylococcus aureus, Staphylococcus epidermidis, Cutibacterium acnes and antibiotic resistant strains, MIC and birth control rate were observed by paper disc method. In the antibacterial activity by the disc diffusion assay against S. aureus, S. epidermidis and C. acnes, the dichloromethane and ethylacetate fraction showed stronger antibacterial activity than the other fractions and extract. Moreover, the ethylacetate fraction showed strong nitric oxide (NO) production inhibitory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cell. In conclusion, we found that B. nivea var. nipononivea extract was not cytotoxic and showed antioxidant, antimicrobial and anti-inflammatory effects. These results suggest that the Boehmeria nivea var. nipononivea extract and fractions could be applied as an effective cosmetic material with antioxidant activity.
Keywords
Boehmeria nivea var. nipononivea; antioxidant; antibacterial; anti-inflammatory; nitric oxide;
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