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http://dx.doi.org/10.15230/SCSK.2018.44.3.277

Beneficial Effect of Collagen-Peptide Mixture with GABA on Improvement Skin and Sleep Quality  

Kim, Jeong Kee (Vitalbeautie Research Institute, Amorepacific Corporation R&D center)
Lim, Seong Hwan (Vitalbeautie Research Institute, Amorepacific Corporation R&D center)
Kim, Wan Gi (Vitalbeautie Research Institute, Amorepacific Corporation R&D center)
Cho, Changhui (Skin Research Institute, IEC Korea)
Ha, Jaehyoun (Skin Research Institute, IEC Korea)
Seo, Dae Bang (Vitalbeautie Research Institute, Amorepacific Corporation R&D center)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.44, no.3, 2018 , pp. 277-284 More about this Journal
Abstract
Collagen peptide plays a protective role in skin by increasing the activity of antioxidant, acts like an activator of skin regeneration by positive feedback and is used as a potent candidate for cosmetics or functional food. GABA acts at inhibitory synapses in the brain by binding to specific transmembrane receptors of both pre- and postsynaptic neuronal processes in vertebrates, is also involved in the synthesis of melatonin and might exert regulatory effects on sleep and reproductive functions. In this study, we investigated the beneficial effect of a mixture of collagen peptide and GABA (J85091900) on skin and sleep condition in woman experiencing sleep disorder. We found that oral supplement with J85091900 significantly decreased the value of Pittsburgh Sleep Quality Index (PSQI), increased sleeping time by 7%, and also improved skin roughness (Ra, Rz, Rt), periorbital wrinkle (Ra, Rt), and skin capacitance in human. These findings indicate that dual strategy with which skin improvement is accomplished using collagen peptide and sleeping well is acquired using GABA could be the novel solution for sleeping beauty by edible cosmetics to improve skin status.
Keywords
collagen peptide; ${\gamma}-aminobutyric$ acid (GABA); sleep disorder; sleeping beauty; edible cosmetics;
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Times Cited By KSCI : 3  (Citation Analysis)
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