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http://dx.doi.org/10.15230/SCSK.2018.44.1.9

A Study on the Whitening Activities of Gentiana scabra Extract  

Lee, Hyun Sang (Mannay Asia R&D Center)
Seok, Ji Hyun (Mannay Asia R&D Center)
Ting, Cheung Wai (Shenzhen Mannay Cosmetics)
Kim, Yun Jeong (Mannay Asia R&D Center)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.44, no.1, 2018 , pp. 9-14 More about this Journal
Abstract
In order to find new functional materials for the cosmetics application, we investigated the anti-oxidant and anti-melanogenic properties of Gentiana scabra extracts (GSE), which were prepared by the various extraction methods. Results showed that GSE had high DPPH radical scavenging activity in a dose-dependent manner. Also, GSE inhibited the prodution of melanin in B16F10 melanoma cell as well as tyrosinase activity. We also found that GSE inhibited mRNA expression of tyrosinase-related protein (TRP)-1 and 2. In conclusion we suggest that GSE is applicable to cosmetics as a potential ingredient for their anti-oxidant and whitening effects.
Keywords
Gentiana scabra extract; anti-oxidant; whitening; tyrosinase; melanin;
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Times Cited By KSCI : 4  (Citation Analysis)
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