Browse > Article
http://dx.doi.org/10.15230/SCSK.2018.44.1.67

Green Tea Root Is a Potential Natural Surfactant and Is Protective against the Detrimental Stimulant PM2.5 in Human Normal Epidermal Keratinocytes  

Na, Hye-Won (AMOREPACIFIC R&D Center)
Lee, Yeongran (AMOREPACIFIC R&D Center)
Park, Jun Seong (AMOREPACIFIC R&D Center)
Lee, Tae Ryoung (AMOREPACIFIC R&D Center)
Kim, Hyoung-June (AMOREPACIFIC R&D Center)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.44, no.1, 2018 , pp. 67-72 More about this Journal
Abstract
Green tea (Camellia sinensis L.) has been widely explored for its medicinal applications. However, most of the studies had targeted the green tea leaf, while other parts remained unexplored. In this study, protective effect of green tea root extract on Normal Human Epidermal Keratinocytes (NHEKs) against the damage induced by an external stimulant (PM2.5) was confirmed. Thirty-year-old green tea root samples were collected from Amorepacific's Dolsongi tea field and green tea root extract was prepared with 70% ethanol. Total crude saponin content in green tea root extract was 54%, which is much higher than that in ginseng extract. Our results suggest that green tea root extract can be used as a natural surfactant in cosmetics. For evaluating its protective effect against the damage induced by PM2.5, IL-36G was used as a biomarker. IL-36G mRNA expression level increased remarkable upon PM2.5 treatment in NHEKs. Moreover, IL-36G was recently reported to be expressed in psoriasis lesions. Results showed significant decrease of IL-36G expression by treatment of green tea root extract. In conclusion, thirty-year-old green tea root extract can be used as a natural surfactant with a high saponin content and may have protective effect against the damage induced by PM2.5.
Keywords
green tea root; natural surfactant; PM2.5; skin care;
Citations & Related Records
연도 인용수 순위
  • Reference
1 C. Trapnell, A. Roberts, L. Goff, G. Pertea, D. Kim, D. R. Kelley, H. Pimentel, S. L. Salzberg, J. L. Rinn, and L. Pachter, Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks, Nat. Protoc., 7(3): 562-78 (2012).   DOI
2 C. Trapnell, L. Pachter, and S. L. Salzberg, TopHat: discovering splice junctions with RNA-Seq, Bioinformatics, 25(9), 1105-1111 (2009).   DOI
3 L. Wang, S. Wang, and L. Wei, RSeQC: quality control of RNA-seq experiments, Bioinformatics, 28, 2184-2185 (2012).   DOI
4 C. Trapnell, B. A. Williams, G. Pertea, A. Mortazavi, G. Kwan, M. J. van Baren, S. L. Salzberg, B. J. Wold, and L. Pachter, Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation, Nat. Biotechnol., 28(5), 511-515 (2010).   DOI
5 E. Uehara, H. Hokazono, M. Hida, T. Sasaki, H. Yoshioka, and N. Matsuo, GABA promotes elastin synthesis and elastin fiber formation in normal human dermal fibroblasts (HDFs), Biosci., Biotechnol., Biochem., 81, 1198-1205 (2017).   DOI
6 A. M. D'Erme, D. Wilsmann-Theis, J. Wagenpfeil, M. Hölzel, S. Ferring-Schmitt, S. Sternberg, M. Wittmann, B. Peters, A. Bosio, T. Bieber, and J. Wenzel, IL-$36{\gamma}$ (IL-1F9) is a biomarker for psoriasis skin lesions, J. Invest. Dermatol., 135, 1025-1032 (2015).   DOI
7 P. Chattopadhyay, S. E. Besra, A. Gomes, M. Das, P. Sur, S. Mitra, and J. R. Vedasiromoni, Anti-inflammatory activity of tea (Camellia sinensis) root extract, Life Sci., 74, 1839-1849 (2004).   DOI
8 S. Hiai, H. Oura, Y. Odaka, and T. Nakajima, A colorimetric estimation of Ginseng saponins, Planta Med., 28, 363-369 (1975).   DOI