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http://dx.doi.org/10.15230/SCSK.2017.43.4.365

Enhancement of Ganodermanondiol and Anti-melanogenesis Effect of Ganoderma lucidum by Rhus verniciflua Extract Supplementation  

Jeong, Yong Un (Department of Biomedical Chemistry, Research Institute for Biomedical & Health Science, College of Biomedical and Health Science, Konkuk University)
Kim, Hong Il (Department of Biomedical Chemistry, Research Institute for Biomedical & Health Science, College of Biomedical and Health Science, Konkuk University)
Kim, Jong Hyun (Department of Biomedical Chemistry, Research Institute for Biomedical & Health Science, College of Biomedical and Health Science, Konkuk University)
Park, Young Jin (Department of Biomedical Chemistry, Research Institute for Biomedical & Health Science, College of Biomedical and Health Science, Konkuk University)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.43, no.4, 2017 , pp. 365-371 More about this Journal
Abstract
This study was carried out to investigate the effect of lacquer tree (Rhus verniciflua) extract on ganodermanondiol (GN), tyrosinase and melanin biosynthesis inhibitor, biosynthesis in Ganoderma lucidum mycelia. In HPLC analysis, GN contents were significantly increased in G. lucidum mycelial extracts supplemented with of 1, 5, 10, and 15% lacquer tree extracts (LTE). In addition, G. lucidum mycelial extracts supplemented with LTEs which had no cytotoxicity activity against B16F10 cells, significantly inhibited melanogenesis in B16F10 cells. GN biosynthesis was facilitated by LTE. Taken together, we propose that G. lucidum mycelial extracts supplemented with LTE can be used as an effective ingredient of skin care products in the future.
Keywords
anti-melanogenesis; Ganoderma lucidum; ganodermanondiol; lacquer tree; Rhus verniciflua;
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