A Study on the Inhibition of Skin Pigmentation by Lobaric Acid as Protease Activated Receptor-2 Antagonist
![]() |
Goo, Jung Hyun
(Department of Genetic Engineering and Graduate School of Biotechnology, Kyung Hee University)
Lee, Ji Eun (Department of Genetic Engineering and Graduate School of Biotechnology, Kyung Hee University) Myung, Cheol Hwan (Department of Genetic Engineering and Graduate School of Biotechnology, Kyung Hee University) Park, Jong Il (Department of Genetic Engineering and Graduate School of Biotechnology, Kyung Hee University) Hwang, Jae Sung (Department of Genetic Engineering and Graduate School of Biotechnology, Kyung Hee University) |
1 | M. Fukuda, T. S. Kuroda, and K. Mikoshiba, Slac2-a/melanophilin, the missing link between Rab27 and myosin va: Implications of a tripartite protein complex for melanosome transport, J. Biol. Chem., 277(14), 12432 (2002). DOI ScienceOn |
2 | M. Strom, A. N. Hume, A. K. Tarafder, E. Barkagianni, and M. C. Seabra, A family of Rab27-binding proteins: Melanophilin links Rab27a and myosin Va function in melanosome transport, J. Biol. Chem., 277(28), 25423 (2002). DOI |
3 | P. G. Joshi, N. Nair, G. Begum, N. B. Joshi, V. P. Sinkar, and S. Vora, Melanocyte-keratinocyte interaction induces calcium signalling and melanin transfer to keratinocytes, Pigment Cell Res., 20(5), 380 (2007). DOI |
4 | M. Seiberg, C. Paine, E. Sharlow, P. Andrade-Gordonb, M. Costanzo, M. Eisinger, and S. S. Shapiro, Inhibition of melanosome transfer results in skin lightening1, J. Invest. Dermatol., 115(2), 162 (2000). DOI |
5 | K. V. D. Bossche, J. M. Naeyaert, and J. Lambert, The quest for the mechanism of melanin transfer, Traffic, 7(7), 769 (2006). DOI |
6 | K. Okazaki, M. Uzuka, F. Morikawa, K. Toda, and M. Seiji, Transfer mechanism of melanosomes in epidermal cell culture, J. Invest. Dermatol., 67(4), 541 (1976). DOI |
7 | G. Scott, S. Leopardi, S. Printup, and B. C. Madden, Filopodia are conduits for melanosome transfer to keratinocytes, J. Cell Sci., 115(Pt 7), 1441 (2002). |
8 | G. Scott and Q. Zhao, Rab3a and SNARE proteins: potential regulators of melanosome movement, J. Invest. Dermatol., 116(2), 296 (2001). DOI |
9 | V. M. Virador, J. Muller, X. Wu, Z. A. Abdel-Malek, Z. X. Yu, V. J. Ferrans, N. Kobayashi, K. Wakamatsu, S. Ito, J. A. Hammer, and V. J. Hearing, Influence of alpha-melanocyte-stimulating hormone and ultraviolet radiation on the transfer of melanosomes to keratinocytes, FASEB J., 16(1), 105 (2002). DOI |
10 | G. Cardinali, S. Ceccarelli, D. Kovacs, N. Aspite, L. V. Lotti, M. R. Torrisi, and M. Picardo, Keratinocyte growth factor promotes melanosome transfer to keratinocytes, J. Invest. Dermatol., 125(6), 1190 (2005). DOI |
11 | L. Minwalla, Y. Zhao, J. Cornelius, G. F. Babcock, R. R. Wickett, I. C. L. Poole, and R. E. Boissy, Inhibition of melanosome transfer from melanocytes to keratinocytes by lectins and neoglycoproteins in an in vitro model system, Pigment Cell Res., 14(3), 185 (2001). DOI |
12 | G. Imokawa, Autocrine and paracrine regulation of melanocytes in human skin and in pigmentary disorders, Pigment Cell Res., 17(2), 96 (2004). DOI |
13 | H. Andoa, Y. Nikib, M. Yoshidaa, M. Itoc, K. Akiyamad, J. H. Kime, T. J. Yoone, M. S. Matsuif, D. B. Yaroshf, and M. Ichihashia, Involvement of pigment globules containing multiple melanosomes in the transfer of melanosomes from melanocytes to keratinocytes, Cellular Logistics, 1(1), 12 (2011). DOI |
14 | R. E. Boissy, Melanosome transfer to and translocation in the keratinocyte, Exp. Dermatol., 12(s2), 5 (2003). DOI ScienceOn |
15 | E. R. Sharlow, C. S. Paine, L. Babiarz, M. Eisinger, S. Shapiro, and M. Seiberg, The protease-activated receptor-2 upregulates keratinocyte phagocytosis, J. Cell Sci., 113(Pt 17), 3093 (2000). |
16 | G. Scott, A. Deng, C. Rodriguez-Burford, M. Seiberg, R. Han, L. Babiarz, W. Grizzle, W. Bell, and A. Pentland, Protease-activated receptor 2, a receptor involved in melanosome transfer, is upregulated in human skin by ultraviolet irradiation, J. Invest. Dermatol., 117(6), 1412 (2001). DOI |
17 | M. Seiberga, C. Painea, E. Sharlowa, P. Andrade-Gordonb, M. Costanzob, M. Eisingera, and S. S. Shapiroa, The protease-activated receptor 2 regulates pigmentation via keratinocyte-melanocyte interactions, Exp. Cell Res., 254(1), 25 (2000). DOI |
18 | O. Dery, C. U. Corvera, M. Steinhoff, and N. W. Bunnett, Proteinase-activated receptors: novel mechanisms of signaling by serine proteases, Am. J. Physiol., 274(6 Pt 1), 1429 (1998). DOI |
19 | C. Paine, E. Sharlow, F. Liebel, M. Eisinger, S. Shapiro, and M. Seiberg, An alternative approach to depigmentation by soybean extracts via inhibition of the PAR-2 pathway, J. Invest. Dermatol., 116(4), 587 (2001). DOI |
20 | C. B. Lin, N. Chen, R. Scarpa, F. Guan, L. Babiarz-Magee, F. Liebel, W. H. Li, M. Kizoulis, S. Shapiro, and M. Seiberg, LIGR, a protease-activated receptor-2-derived peptide, enhances skin pigmentation without inducing inflammatory processes, Pigment Cell Melanoma Res., 21(2), 172 (2008). DOI |
![]() |