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http://dx.doi.org/10.15230/SCSK.2014.40.2.133

Stable Liquid Paraffin-in-Water Nanoemulsions Prepared by Phase Inversion Composition Method  

Kim, Eun Hee (Basic Medicine Department, College of Medical Sciences, Jeonju University)
Cho, Wan Goo (Basic Medicine Department, College of Medical Sciences, Jeonju University)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.40, no.2, 2014 , pp. 133-139 More about this Journal
Abstract
Oil-in-water nanoemulsions were prepared in the system of water/Span 80-Tween 80/long-chain paraffin oil via the PIC (phase inversion composition) method. With the increase of preparation temperature from $30^{\circ}C$ to $80^{\circ}C$, the diameter of emulsion droplets decreased from 120 nm to 40 nm, proving the formation of nanoemulsions. By varying the HLB (hydrophilic lipophilic balance) of mixed surfactants, we found that there was an optimum HLB around 12.0 ~ 13.0 corresponding to the minimum droplet size. The viscosity of nanoemulsions clearly increased with droplet volume fraction, f, but the droplet size slightly increased. Significantly, at ${\phi}{\leq}0.3$, the size distribution of nanoemulsions kept constant more than 2 months. These results proved that the viscous paraffin oil can hardly be dispersed by the PIC method at $30^{\circ}C$, but the increase in preparation temperature makes it possible for producing monodisperse nanoemulsions. Once the nanoemulsion is produced, the stability against Ostwald ripening is outstanding due to the extremely low solubility of the liquid paraffin oil in the continuous phase. The highly stable nanoemulsions are of great importance in cosmetic applications.
Keywords
Liquid paraffin; Nanoemulsion; PIC; Ostwald ripening; Cosmetics;
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