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http://dx.doi.org/10.15230/SCSK.2013.39.1.019

Biological Potential of Enzymatic and Polyphenol Extracts from Ecklonia cava  

Lee, Su Min (R&D Center of Skin Science and Cosmetics, Enprani Co. Ltd.)
Kim, Jin Eun (R&D Center of Skin Science and Cosmetics, Enprani Co. Ltd.)
Oh, Myoung Jin (R&D Center of Skin Science and Cosmetics, Enprani Co. Ltd.)
Lee, Joo Dong (R&D Center of Skin Science and Cosmetics, Enprani Co. Ltd.)
Jeon, You-Jin (Department of Marine Life Science, Jeju National University)
Kim, Bora (R&D Center of Skin Science and Cosmetics, Enprani Co. Ltd.)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.39, no.1, 2013 , pp. 19-24 More about this Journal
Abstract
To investigate the efficacy of enzymatic extract of Ecklonia cava and its polyphenol extract (AG-DK) as cosmetic ingredients, the anti-oxidative effect, anti-glycation effect, anti-melanogenic effect, and anti-inflammatory effect of the extracts were evaluated in vitro. The enzymatic extract of E. cava ($SC_{50}$ 42.9 ppm) and AG-DK ($SC_{50}$ 6.4 ppm) showed a strong DPPH free radical scavenging activity. The anti-glycation ability of the enzymatic extract of E. cava and AG-DK was tested using bovine serum albumin (BSA), which inhibited the formation of advanced glycation end-products (AGEs) in the BSA/glucose system. The enzymatic extract of E. cava ($IC_{50}$ 97.2 ppm) and AG-DK ($IC_{50}$ 7 ppm) had inhibitory effects on tyrosinase activity. Moreover, the enzymatic extract of E. cava and AG-DK had an anti-inflammatory effect through the inhibition of nitricoxide (NO) and prostaglandin E2 ($PGE_2$). These findings suggest that the enzymatic extract of E. cava and AG-DK can be applied to skin-care products as cosmetic ingredients.
Keywords
Ecklonia cava extracts; anti-oxidant; anti-glycation; tyrosinase inhibition; anti-inflammation;
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