The New in vitro Oral Irritation Test Method for Toothpaste using YD-38 Oral Mucosal Cell Line
![]() |
Nam, Gi Baeg
(R&D Center, Amorepacific Coporation)
Cho, Sun-A (R&D Center, Amorepacific Coporation) Cho, Jun-Cheol (R&D Center, Amorepacific Coporation) Kim, Chanho (R&D Center, Amorepacific Coporation) Kim, Yoo-Jin (R&D Center, Amorepacific Coporation) Lee, John Hwan (R&D Center, Amorepacific Coporation) Shin, Kyeho (R&D Center, Amorepacific Coporation) |
1 | I. Rantanen, K. Jutila, I. Nicander, J. Tenovuo, and E. Soderling, The effects of two sodium lauryl sulphate- containing toothpastes with and without betaine on human oral mucosa in vivo, Swedish Denal Journal, 27, 31 (2003). |
2 | E. E. Ahlfors, J. E. Dahl, and T. Lyberg, The development of T cell-dominated inflammatory responses induced by sodium lauryl sulphate in mouse oral mucosa, Archives of oral biology, 57(6), 796 (2012). DOI ScienceOn |
3 | E. Ahlfors and C. Czerkinsky, Contact sensitivity in the murine oral mucosa. I. An experimental model of delayed-type hypersensitivity reactions at mucosal surfaces, Clin Exp Immunol., 86(3), 449 (1991). DOI ScienceOn |
4 | P. Bourrinet, JP. Conduzorgues, H. Dutertre, J. Macabies, P. Masson, J. Maurin, and O. Mercier, Interlaboratory study for the assessment of potential irritative properties of hygiene products on the hamster cheek pouch, Lab Anim. Sci., 45(1), 36 (1995). |
5 | R. J. Veys, J. H. Baert, and J. A. De Boever, Histological changes in the hamster cheek pounch epithelium induced by topical application of sodium laul sulphate, Int. J. Path., 75, 203 (1994). |
6 | M. Klausner, S. Ayehunie, B. A. Breyfogle, P. W. Wertz, L. Bacca, and J. Kubilus, Organotypic human oral tissue models for toxicological studies, Toxicology in Vitro, 21, 938 (2007). DOI ScienceOn |
7 | T. Tsutsui, Y. Tanaka, A. Ushimura, T. Ide, M. Matsumura, and J. C. Barrett, In vitro cytotoxicity of diverse preparations used in dental practice to human gingival keratinocytes, Toxicology in Vitro, 11(4), 393 (1997). DOI ScienceOn |
8 | K. Moharamzadeh, H. Colley, C. Murdoch, V. Hearnden, W. L. Chai, I. M. Brook, M. H. Thornhill, and S. MacNeil, Tissue-engineered Oral Mucosa, Journal of Dental Research, 86, 115 (2007). DOI ScienceOn |
9 | J. P. Babich and H. Babich, Sodium lauryl sulfate and triclosan : In vitro cytotoxicity studies with gingival cells, Toxicology Letters, 91(3), 189 (1997). DOI ScienceOn |
![]() |