Browse > Article

Anti-aging and Anti-melanogenesis Efficacy by Antioxidative Mineral-bio Water  

Choi, Hyun-Kyung (Department of Chemical and Biochemical Engineering, Dongguk University)
Oh, Myoung-Jin (Department of Chemical and Biochemical Engineering, Dongguk University)
Her, Myeong-Jun (Miba Corp.)
Kyeong, Kyeong-Hwan (Miba Corp.)
Park, Chang-Seo (Department of Chemical and Biochemical Engineering, Dongguk University)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.35, no.1, 2009 , pp. 57-63 More about this Journal
Abstract
UV irradiated skin cells produce reactive oxygen species (ROS). ROS is known to be the primary cause of skin inflammation that is eventually leading to skin aging through decrease of collagen in the dermis. In this study, we evaluated basic efficacy of anti-aging, anti-inflammation and anti-melanogenesis using two antioxidative mineral-bio waters (Mineral-bio water 1 (MIBA-W1) and Mineral-bio water 2 (MIBA-W2)). Both antioxidative mineral-bio waters reduced TNF-${\alpha}$ expression which was induced upon UV irradiation. MIBA-W 1 increased collagen synthesis from UVB irradiated fibroblast at 0.01 % concentration but MIBA-W2 shows slight, but linear increase. Stimulation of melanogenesis by ${\alpha}$-MSH treatment in the cultured B16-F1 melanoma was significantly reduced by the treatment of MIBA-W2 in a dose dependent manner. Taken together, antioxidative MIBA-W1 and 2 seem to have potential applications as functional cosmetic materials.
Keywords
antioxidative mineral-bio water; TNF-${\alpha}$; collagen synthesis; melanin; B16-F1 melanoma;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 J. Y. Seo, Skin aging from phenotype to mechanism, Korean J. Invest. Dermatol., 8(4), 187 (2001)
2 J. H. Chung, V. N. Hanft, and S. Kang, Aging and photoaging, J. American Acad. Dermatol., 49(4), 69 (2003)
3 M. H. Shin, $H_2O_2$ accumulation by catalase reduction changes MAP kinase signaling in aged human skin in vivo, J. Invest. Dermatol., 125(2), 221 (2005)   DOI   PUBMED   ScienceOn
4 T. Ishida and I. Sakaguchi, Protection of human keratinocytes from UVB-induced inflammation using root extract of Lithospermum erythrorhizon, Biol. Pharm. Bull., 30(5), 928 (2007)   DOI   ScienceOn
5 G. J. Fisher and J. J. Voorhees, Molecular mechanisms of photoaging and its prevention by retinoic acid: ultraviolet irradiation induces MAP kinase signal transduction cascades that induce AP-1-regulated matrix metalloproteinases that degrade human skin in vivo, J. Investig. Dermatol. Symp. Proc., 3(1), 61 (1998)   ScienceOn
6 M. Seiberg, C. Paine, E. Sharlow, P. Andrade-Gordon, M. Costanzo, and M. Eisinger, Inhibition of melanosome transfer results in skin lightening, J. Invest. Dermatol., 115(2), 162 (2000)   DOI   ScienceOn
7 D. H. Nguyen, D. T. M. Nguyen, L. H. La, S. H. Yang, H. B. Lee, R. J. Kim, J. H. Shin, D. M. Kim, and E. K. Kim, Depigmenting effect of Cinnamomum cassia Presl in B16F10 melanoma cells, Korean J. Chem. Eng., 24(5), 827 (2007)   DOI   ScienceOn
8 F. Cimino, M. Cristani, A. Saija, F. P. Bonina, and F. Virgili, Protective effects of a red orange extract on UVB-induced damage in human keratinocytes, Biofactors, 30(2), 129 (2007)   DOI   ScienceOn
9 S. L. Camhi, P. Lee, and A. M. Choi, The oxidative stress response, New Horiz, 3(2), 170 (1995)   ScienceOn
10 L. Rittie and G. J. Fisher, UV-light-induced signal cascades and skin aging, Ageing Res. Rev., 1(4), 705 (2002)   DOI   ScienceOn
11 L. D. P. Uyen, D. H. Nguyen, and E. K. Kim, Mechanism of skin pigmentation, Biotechnology and Bioprocess Engineering, 13(4), 383 (2008)   DOI   ScienceOn
12 Y. Aoki, T. Tanigawa, H. Abe, and Y. Fujiwara, Melanogenesis inhibition by an oolong tea extract in B16 mouse melanoma cells and UV-induced skin pigmentation in brownish guinea pigs, Bioscience Biotechnology and Biochemistry, 71(8), 1879 (2007)   DOI   ScienceOn
13 A. Grone, Keratinocytes and cytokines, Vet. Immunol. Immunopathol, 88(1-2), 1 (2002)   DOI   PUBMED   ScienceOn
14 G. J. Fisher, Z. Q. Wang, S. C. Datta, J. Varani, S. Kang, and J. J. Voorhees, Pathophysiology of premature skin aging induced by ultraviolet light, N. Engl. J. Med., 337(20), 1419 (1997)   DOI   ScienceOn
15 M. M. Bashir, M. R. Sharma, and V. P. Werth, TNF-$\alpha$ production in the skin, Arch. Dermatol. Res., (2008)   DOI   PUBMED   ScienceOn
16 M. Yoshimura, Y. Watanabe, K. Kasai, J. Yamakoshi, and T. Koga, Inhibitory effect of an ellagic acid-richpomegranate extract on tyrosinase activity and ultraviolet-induced pigmentation, Bioscience Biotechnology and Biochemistry, 69(12), 2368 (2005)   DOI   ScienceOn