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Application as a Cosmeceutical Ingredient of Extract from Euphorbia jolkini  

Lee, Dae-Woo (R&D Center, Charmzone)
Kim, Young-Jin (R&D Center, Charmzone)
Kim, Young-Sil (R&D Center, Charmzone)
Eom, Sang-Yong (R&D Center, Charmzone)
Kim, Jong-Heon (R&D Center, Charmzone)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.33, no.4, 2007 , pp. 275-280 More about this Journal
Abstract
In this study, we evaluate anti-oxidation, whitening and anti-inflammatory efficacies of Euphorbia jolkini extract for application as a cosmeceutical ingredient. We separated 5 fractions from Euphorbia jolkini extract (70 % MeOH) by MPLC. First and 5th fractions showed a supressive effect on Mn-SOD synthesis in the normal human fibroblasts. They inhibited melanogensis in the B16-F10 melanma cells. Furthermore, 1st and 5th fractions reduced the amounts of $IL-1{\alpha}$, IL-6, COX-II and total NO secreted from the normal human fibroblasts. These results suggest that Euphorbia jolkini extract may be used as an active ingredient in cosmetics.
Keywords
Euphorbia jolkini; whitening; anti-inflammation; $IL-1{\alpha}$; IL-6;
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