Browse > Article

Trend of Depigmenting Research Based on Patent Analysis  

Kim, Eun-Ki (Department of Biological Engineering, Inha University, Naitonal Research Laboratory, Skin-Bioactive Materials Laboratory)
Lee, Hyang-Bok (5T International Patent Law Firm)
Lee, Haeng-Byoung (5T International Patent Law Firm)
Lee, Cheo-Young (Department of Biological Engineering, Inha University, Naitonal Research Laboratory, Skin-Bioactive Materials Laboratory)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.33, no.4, 2007 , pp. 209-217 More about this Journal
Abstract
Melanin plays an important role in protecting human skin from UV radiation and determines the race and skin color. Melanin is also major target for developing skin-whitening cosmeceuticals. Recently, as the market size of skin-whitening cosmeceuticals has rapidly expanded, related researches and developments are also focused on maximizing the safety and efficacy. Also, patents of skin-whitening materials have been increasing steadily for ensuring the competitive power. Patent also shows the research trend of industry and institutes. In this review, we analyze the trend of research and development based on the patent application of skin-whitening cosmeceuticals.
Keywords
antioxidant; cosmetic; skin; melanin; whitening agent;
Citations & Related Records
연도 인용수 순위
  • Reference
1 S. Ito, The IFPCS presidential lecture: a chemist's view of melanogenesis, Pigment Cell Res., 16, 230 (2003)   DOI   ScienceOn
2 E. Steingrimsson, N. G. Copeland, and N. A. Jenkins, Melanocytes and the microphthalmia transcription factor network, Annual Review of Genetics, 38, 365 (2004)   DOI   ScienceOn
3 L. Stryer, Biochemistry, Freeman, New York, USA (1998)
4 H. Saito, K. Yasumoto, K. Takeda, K. Takahashi, H. Yamamoto, and S. Shibahara, Microphthalmia-associated transcription factor in the wnt signaling pathway, Pigment Cell Res., 16, 261 (2003)   DOI   ScienceOn
5 P. Besmer, J. E. Murphy, P. C. Geroge, F. H. Qiu, P. J. Bergold, L. Lederman, H. W. Jr. Snyder, D. Brodeur, E. E. Zuckerman, and W. D. Hardy, A new acute transforming feline retrovirus and relationship of its oncoben v-kit with the protein kinase gene family, Nature, 320, 415 (1986)   DOI   ScienceOn
6 S. J. Gadd and L. K. Ashman, A murine monoclonal antibody specific for a cell-surface antigen expressed by a subgroup of human myeloid leukaemias, Leukoc. Res., 9, 1329 (1985)   DOI   ScienceOn
7 Y. Yarden, W. J. Kuang, T. Yang-Feng, L. Coussens, S. Munemitsu, T. J. Dul, E. Chen, J. Schlessinger, U. Francke, and A. Ullrich, Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand, EMBO J., 6, 3341 (1987)   PUBMED
8 R. Halaban, The regulation of normal melanocyte proliferation, Pigment Cell Res., 13, 4 (2000)   DOI   ScienceOn
9 E. R. Price and D. E. Fisher, Sensorineural deafness and pigmentation genes melanocytes and the MITF transcriptional network, Neuron, 30, 15 (2001)   DOI   ScienceOn
10 R. E. Boissy, C. Sakai, H. Zhao, T. Kobayashi, and V. J. Hearing, Human tyrosinase related protein-1 (TRP-1) does not function as a DHICA oxidase activity in contrast to murine TRP-1. Exp. Dermatol., 7, 198 (1998)   DOI   ScienceOn
11 L. Kos, C. Ponzetto, G. Merlino, and W. Pavan, MET-HGF signaling is critical for melanocyte development: Implications for Waardenburg syndrome Type II. Pigment Cell Res., 10, 107 (1997)
12 R. G. Colin, Cells in focus. Melanocytes: The new Black, Int. J. Biochem Cell Biol., 39, 275 (2007)   DOI   PUBMED   ScienceOn
13 J. Pawelek, M. Sansone, N. Koch, G. Christie, R. Halaban, J. Hendee, A. B. Lerner, and J. M. Varga, Melanoma cells resistant to inhibition of growth by melanocyte stimulating hormone, Proc. Natl. Acad. Sci. USA, 72, 951 (1975)
14 S. Shibahara, K. Takeda, K. Yasumoto, T. Udono, K. Watanabe, H. Saito, and K. Takahashi, Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function and regulation, J. Invest. Dermatol. Sym. Proc., 6, 99 (2001)
15 S. Laporte, J. B. Denault, P. D'Orleans-Juste, and R. Leduce, Presence of furin mRNA in cultured bovine endothelial cells and possible involvement of furin in the processing of the endothelin precursor, J. Cardiovasc. Pharmacol. 22 Supl., 8, S7 (1993)   PUBMED
16 S. S. Shola and E. K. Barbara, The Biology of Melanocytes. Review article, Vet. Dermatol., 14, 57 (2003)   DOI   ScienceOn
17 H. R. Widlund and D. E. Fisher, Microphthalmia-associated transcription factor: a critical regulator of pigment cell development and survial, Oncogene, 22, 3035 (2003)   DOI   ScienceOn
18 T. Kunisada, H. Yamazaki, T. Hirobe, S. Kamei, M. Omoteno, H. Tagaya, H. Hemmi, U. Koshimizu, T. Nakamura, and S. I. Hayashi, Keratinocyte expression of transgenic hepatocyte growth factor affects melanocyte development, leading to dermal melanocytosis, Mech. Dev., 94, 67 (2000)   DOI   PUBMED   ScienceOn
19 C. B. Duarte and C. S. Miguel, The melanosome as a model to study organelle Motility in mammals. review: pigment gene focus, Pigment Cell Res., 17, 111 (2004)   DOI   ScienceOn
20 J. L. Bolognia and S. J. Qrlow, Biology of melanocytes, Dermatology, Mosby, Chicago, USA (2005)
21 L. Kos, A. Aronzon, H. Takyama, F. Maina, C. Ponzetto, G. Merlbvo, and W. Pavani, Hepatocyte growth factor/scatter factor-MET signaling in neural crest-derived melanocyte development, Pigment Cell Res., 12, 1 (1999)   DOI
22 J. M. Pawelek, After dopachrome? Pigment Cell Res., 4, 53 (1991)   DOI   ScienceOn
23 A. Hachiya, T. Kobayashi, Y. Takema, and G. Imokawa, Biochemical characterization of endothelin-converting enzyme-alpha in culture skin-derived cells and its postulated role in the stimulation of melano-genesis in human epidermis, J. Biol. Chem., 277, 5395 (2002)   DOI   ScienceOn
24 G. Prota, Melanins and melanogenesis, ed. H. B. Jovanovich, 4, Academic Press, San diego, New York (1992)
25 A. Inoue, M. Yanagisawa, S. Kimura, Y. Kasuya, T. Miyauchi, K. Goto, and T. Masaki, The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes, Proc. Natl. Acad. Sci. USA, 86, 2863 (1989)