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Application as a Cosmeceutical Ingredient of Methanolic Extract from Ardisia crenata  

Lee, Dae-Woo (R&D Center, Charmzone)
Kim, Young-Jin (R&D Center, Charmzone)
Kim, Young-Sil (R&D Center, Charmzone)
Eom, Sang-Yong (R&D Center, Charmzone)
Kim, Jong-Heon (R&D Center, Charmzone)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.32, no.4, 2006 , pp. 249-255 More about this Journal
Abstract
In this study, we evaluated anti-oxidation, whitening and anti-inflammatory effects of Ardisia crenata for use as the cosmeceuticals. Ardisia crenata extract (70% MeOH) showed a significant free-radical scavenging effect (up to 90% over at the concentration of 0.01 %) against DPPH radical generation and showed a significant inhibitory effect (up to 50% over at the concentration of 0.05 %) on melanin synthesis in B16 meanoma cells. We separated 5 fractions from Ardisia crenata extract (70% MeOH) by MPLC. The 3rd, 4th, and 5th fractions showed the anti-oxidation (DPPH radical scavenging activity and supressive effect on Mn-SOD), whitening (inhibitory effect on melanin synthesis) and anti-inflammatory (supressive effects on $IL-1{\alpha}$, IL-6, COX-2 and total NO synthesis) effects.
Keywords
Ardisia crenata; anti-oxidation; melanogenesis; anti-inflammation; $IL-1{\alpha}$;
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