Browse > Article

The Study for Antioxidative Effects of Acanthopanax sessiliflorus Extract as a New Cosmetics Ingredients Using Electron Paramagnetic Resonance  

Choi, Shin-Wook (Radiant Inc., Bioindustry Foundation)
Kim, Chang-Su (Radiant Inc., Bioindustry Foundation)
Choi, Myoung-Soo (R&D Center, Somang Cosmetics Co.)
Kim, Bo-Hyeon (R&D Center, Somang Cosmetics Co.)
Kim, Hack-Soo (R&D Center, Somang Cosmetics Co.)
Choi, Dae-Sung (Jeongseon Agricultural Technology & Extension Center)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.31, no.1, 2005 , pp. 73-78 More about this Journal
Abstract
This work was carried out to investigate the antioxidative effects of Acanthopnax sessiliflorus from Jeongseon County for the purpose of development of a novel antioxidant from natural products. The antioxidant activity was determined by using electron paramagnetic resonance (EPR), not measuring the radical scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) which have bun used for antioxidant activity of natural sources. Although DPPH radical scavenging activity assay have been generally used for antioxidant activity, this assay is nut appropriated for determinating which radical is scavenged by extracts from natural products. Using EPR, we determinated whether A. sessiliflorus extracts from Jeongseon County scavenge specific radicals or not. On experiment of scavenging superoxide anion radical, hydroxyl radical, nitrogen dioxide and peroxinitrite. Extracts from A. sessiliflorus showed high antioxidant activities to reactive oxygen and nitrogen species. These result suggest that extracts from A. sessiliflorus act as an antioxidant by scavenging reactive oxygen and nitrogen species and used as new cosmetic ingredients for anti-oxidative stress in skin.
Keywords
electron paramagnetic resonance; antioxidants; free radical; acanthopanax sessiliflorus; plant extracts;
Citations & Related Records
연도 인용수 순위
  • Reference
1 M. M. Corl, Toxicological and biochemistry of butylated hydroxyanisole and butylated hydroxytoluene, J. Am Oil Chem Soc, 52(1), 59 (1975)   DOI
2 김창민, 신민교, 안덕균, 이경순, 완역중약대사전, 3907, 도서출판 정담, 서울 (1998)
3 M. Miyakoshi, Y. Ida, S. Isoda, and J. Shoji, Alpha-hydroxyoleanane-type triterpene glycosyl esters from leaves of Aamihopanax spinosus, Phytochemistry, 34(6), 1599 (1993)   DOI   ScienceOn
4 A. Ghiselli, M. Serafini, G. Maiani, E. Azzini, and A. Ferro-Luzzi, A fluorescence-based methods for measuring total plasma antioxidant capability, Free Rad. Biol. Med, 18(1), 29 (1995)   DOI   ScienceOn
5 S. K. Kim, Y. G. Kim, M. K. Lee, J. S. Ham, J. H. Lee, and H. Y. Lee, Comparison of biological activity according to extracting solvents of four Acanthopananx root bark, Korean J. Medical Corp. Sci, 8(1), 21 (2000)
6 J. K. Ahn, W. Y. Lee, S. J. Oh, Y. H. Park, S. D. Hur, and M. S. Choi, The contents of chlorogeic acid and eluthersoside E in Eleutherococcus senticocus (Ruper. et Maxim) Harms, J. Korean For. Soc, 89(2), 211 (2000)
7 Y. Q. Zhao, S. S. Yang, J. H. Liu, and G. R. Zhao, Chemical constitutents of Acanihopanax senticocus (Rupt. et Maxim) Harms, Zhongguo Zhong Yao Za Zhi, 18(7), 428 (1993)
8 P. Ody, Herbal insights - A close look at active constituents of medical herbs, SOFE Journal, 121, 8 (1995)
9 H. Sawada, M. Miyakoshi, S. Isoda, Y. Ida, and J. Shoji, Saponins from leaves of Acanthopanax sie-boldianus, Phytochernisty, 34(4), 1117 (1993)
10 Y. H. Choi, M, J. Kim, H. S. Lee, B. S. Yun, C. Hu, and S. S. Kwak, Antioxidative compounds in aerial parts of Potentilla fragarioides, Kor. J. Pharmacon, 31(1), 79 (1998)
11 J. H. lung, S. W. Choi, and S. Han, Screening for antioxidative effects of cultivated crop from jeongsean county using electron paramagnetic resonance, J. Sanhakyeon Reg. Consortium Center, Kangwon Nat'l Univ., 7, 23 (2003)
12 E. A. Lissi, M. Salim-Hanna, C. Psacual, and M. D. Castillo, Evaluation of total antioxidant potencial and total reactivity from lurninol-enhanced chemiluminescence measurements, Free Radic. Biol. Med, 18(2), 153 (1995)   DOI   ScienceOn
13 J. Z. Wang, H. Tsumura, N. Ma, K. Shimura, and H. Ito, Biochemical and morphological alterations of macrophages and spleen cells produced by antitumor polysaccharide from Acanihopanax obovatus roots, Planta Med., 59(1), 54 (1993)