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Surface Chemistry in Biocompatible Nanocolloidal Particles  

Kim Jong-Duk (Department of Chemical & Biomolecular Engineering, Korea Advanced Institute of Science and Technology)
Jung Jae Hyun (Department of Chemical & Biomolecular Engineering, Korea Advanced Institute of Science and Technology)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.30, no.3, 2004 , pp. 295-305 More about this Journal
Abstract
Colloid and surface chemistry have been focused on surface area and surface energy. Local surface properties such as surface density, interaction, molecular orientation and reactivity have been one of interesting subjects. Systems of such surface energy being important would be listed as association colloid, emulsion, particle dispersion, foam, and 2-D surface and film. Such nanoparticle systems would be applied to drug delivery systems and functional cosmetics with biocompatible and degradable materials, while nanoparticles having its size of several nm to micron, and wide surface area, have been accepted as a possible drug carrier because their preparation, characteristics and drug loading have been inves-tigated. The biocompatible carriers were also used for the solubilization of insoluble drugs, the enhancement of skin absorption, the block out of UV radiation, the chemical stabilization and controlled release. Nano/micro emulstion system is classified into nano/microsphere, nano/microcapsule, nano/microemulsion, polymeric micelle, liposome according to its prep-aration method and size. Specially, the preparation method and industrial applications have been introduced for polymeric micelles self-assembled in aqueous solution, nano/microapsules controlling the concentration and activity of high concen-tration and activity materials, and monolayer or multilayer liposomes carrying bioactive ingredients.
Keywords
nano/microsphere; nano/microcapsule; nano/microemulsion; polymer micelle; liposome;
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