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Anti-wrinkle Effect of Safflower (Carthamus tinctorius) Seed Extract (I)  

윤경섭 ((주)사임당화장품 기술연구소)
김미진 ((주)사임당화장품 기술연구)
김자영 ((주)사임당화장품 기술연구)
최상원 (대구가톨릭대학교 식품영양학)
홍진태 (충북대학교 약학과)
Publication Information
Journal of the Society of Cosmetic Scientists of Korea / v.30, no.1, 2004 , pp. 15-22 More about this Journal
Abstract
Anti-wrinkle Effect of safflower (Carthamus tinctorius L.) seed extract (CTSE) was evaluated by determination of the anti-oxidation, collagen synthesis and elastase inhibition in normal human fibroblast. CTSE showed anti-oxidation and collagen synthesis ability as much as or greater than other phytoestrogenic compounds such as genistein or resveratrol. Consistent with collagen synthesis promotion, CTSE also showed inhibitory effect on elastase activity. In the human skin irritation test, 0.2% CTSE did not show any adverse effect. These results demonstrate that CTSE can be useful as an anti-wrinkle cosmetic ingredient.
Keywords
anti-wrinkle effect; safflower (Carthamus tinctorius L.) seed extract; anti-oxidation; collagen synthesis; elastase inhibition;
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