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http://dx.doi.org/10.15432/JKTO.2019.24.1.001

A Case Report of Advanced Non-Small Cell Lung Cancer Patient Treated with Samchilchoongcho-Jung in Conjunction with Alectinib  

Ko, Myung-hyun (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University)
Myong, Ji-soo (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University)
Park, So-jung (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University)
Jeon, Hyung-joon (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University)
Lee, Yeon-weol (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University)
Cho, Chong-kwan (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University)
Yoo, Hwa-seung (East West Cancer Center, Dunsan Korean Medicine Hospital of Daejeon University)
Publication Information
Journal of Korean Traditional Oncology / v.24, no.1, 2019 , pp. 1-9 More about this Journal
Abstract
Objective: The purpose of this study is to report the clinical effectiveness of advanced non-small cell lung cancer (NSCLC) with Samchilchoongcho-Jung (HAD-B1) in conjunction with Alectinib. Methods: The patient was diagnosed with Anaplastic lymphoma kinase (ALK) mutated (2+) non-small cell lung cancer adenocarcinoma stage IV, suffering from edema of lower extremities, dyspnea, pleural effusion, general weakness, insomnia. The patient being treated with Alectinib was treated with Samchilchoongcho-Jung (HAD-B1) for disease control and symptom management. The clinical outcomes were measured by National Cancer Institute Common Terminology Criteria for Adverse Event (NCI-CTCAE), Numeral rating scale (NRS) and Eastern Cooperative Oncology Group (ECOG). Results: After treatment, dyspnea and edema of lower extremities was relieved from NRS 7 to 5, and 6 to 1 respectively. And ECOG score of the patient was improved from grade 3 to 2. During and after treatment, we didn't find any severe toxicities on laboratory findings. Conclusion: This case study suggests that Samchilchoongcho-Jung (HAD-B1) may improve symptom relief and life quality of NSCLC patient in conjunction with Alectinib.
Keywords
Non-small cell lung cancer; adenocarcinoma; ALK mutated; Herbal Medicine; Quality of Life; Alectinib; pleural effusion;
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Times Cited By KSCI : 5  (Citation Analysis)
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