Browse > Article
http://dx.doi.org/10.7778/jpkm.2022.36.2.26

A Scoping Review of Herbal Medicine for Depression in Adolescents and Young Adults  

Kim, Ye Ji (Department of Pediatrics, Kyung Hee University Korean Medicine Hospital)
Seo, Hae Sun (Department of Korean Pediatrics, Graduate School, Kyung Hee University)
Kim, Sang Min (Department of Pediatrics, Kyung Hee University Korean Medicine Hospital)
Lee, Sun Haeng (Department of Pediatrics, Kyung Hee University Korean Medicine Hospital)
Lee, Jin Yong (Korea Institute of Oriental Medicine)
Publication Information
The Journal of Pediatrics of Korean Medicine / v.36, no.2, 2022 , pp. 26-39 More about this Journal
Abstract
Objectives The purpose of this study was to collect reported but scattered data on herbal medicine treatment for depression in adolescents and young adults and to establish future research directions for this topic. Methods Using the scoping review method, 10 Korean and foreign databases were searched for studies published up to March 22, 2022. Studies targeting children and adolescents diagnosed with depression, studies using herbal medicine treatments, and clinical studies were included. Results Twelve randomized clinical trials, two chart reviews, and six case reports were identified. Frequently used Korean medical patterns, treatment methods, herbal medicines, decoctions, treatment periods, and post-treatment evaluation results were analyzed. Differences in the confirmed results from actual clinical settings were reviewed, and the direction of follow-up research on this topic was suggested. Conclusions This study outlined the results of various levels of clinical research on herbal medicine treatment for depression in adolescents and young adults, showed the clinical availability of herbal medicine, and provided a foundation for future research.
Keywords
Depression; Adolescents; Herbal medicine; Korean medicine; Scoping review;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
연도 인용수 순위
1 Ai X, Zhang SZ. Juvenile depression treated with acupuncture combined with Dushuwan. J Liaoning Univ TCM. 2013;15(9):89-90.
2 Song YX, Huo J. Sertraline plus Shumian capsules and sertraline alone in the treatment of adolescent depression. Chin J Mod Drug App. 2014;8(9):139-40.
3 Tao BP, Geng S, Wang YH. Observation on the curative effect of Shuganjieyu capsule in the treatment of adolescent depression. Zhejiang J Integr Tradit Chin West Med. 2015;25(5):464-5.
4 He SQ, Gao PH. Clinical study on Jieyu Anshen decoction combined with electroacupuncture in the treatment of adolescent depression. World Latest Med Inf. 2017;17(40):95-6.
5 Cheng SY, Ma HX, Zhao Y, Yuan J. Clinical observation on 40 cases of teenage depression treated by combination of traditional chinese and western medicine. Shandon Med J. 2012;52(4):58-9.   DOI
6 Qi JH, Liu J, Zhou XL, Qin LX, Liang YS, Zhang DX, Zhou YN, Yang W, Xie J, Xie HW. Discussion of the clinical efficacy of acupuncture plus chaihu guizhi ganjiang decoction for teenage depression based on infrared thermal imaging technology. Shanghai J Acu Moxi. 2019;38(11):1219-24.
7 Wang HF, Xiang XH. Observation on the application effect of TCM health intervention in adolescent depression patients in colleges and universities. Front Med. 2021;11(27):5,6,9.
8 Wang F, Zhao J. 1 case of depression treated with Bukan yili dan modified and subtracted. World Latest Med Inf. 2019;19(16):243.
9 Lin S. Analysis of TCM syndrome characteristics and curative effect of children's depression. Fujian J TCM. 2004;35(1):12-3.
10 Ku F. Depressed people should replenish yang qi. Public Health. 2021(12):69.
11 Wang Y, Huang M, Lu X, Wei R, Xu J. Ziziphi spinosae lily powder suspension in the treatment of depression-like behaviors in rats. BMC Complement Med Ther. 2017;17(1):1-10.   DOI
12 Ye MR. Effect observation on treating adolescent depressive disorder in the integrative medicine. Clin J Chin Med. 2013(1):46.   DOI
13 Simon GE. The antidepressant quandary - considering suicide risk when treating adolescent depression. N Engl J Med. 2006;355(26):2722-3.   DOI
14 American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th edition. Arlington, VA: American Psychiatric Association; 2013:155-88.
15 Kim IR, Kim HC, Kuk YB, Park SJ, Park YG, Park JH, Seo BI, Seo YB, Song HJ, Shin MK, Lee YJ, Lee YC, Lee JH, Lim GH, Jo SI, Jung JG, Joo US, Choi HY. Bonchohak. 3rd ed. Seoul: Young Lim Publishing Co. 2010:186-8, 530-2.
16 Weinberger AH, Gbedemah M, Martinez AM, Nash D, Galea S, Goodwin RD. Trends in depression prevalence in the USA from 2005 to 2015: widening disparities in vulnerable groups. Psychol Med. 2018;48(8):1308-15.   DOI
17 Siu AL. Screening for depression in children and adolescents: US Preventive Services Task Force recommendation statement. Pediatrics. 2016;137(3):e20154467   DOI
18 Rice F, Riglin L, Lomax T, Souter E, Potter R, Smith DJ, Thapar AK, Thapar A. Adolescent and adult differences in major depression symptom profiles. J Affect Disord. 2019;243:175-81.   DOI
19 Asarnow JR, Jaycox LH, Duan N, LaBorde AP, Rea MM, Tang LQ, Anderson M, Murray P, Landon C, Tang B. Depression and role impairment among adolescents in primary care clinics. J Adolesc Health. 2005;37(6):477-83.   DOI
20 Miller L, Campo JV. Depression in adolescents. N Engl J Med. 2021;385(5):445-9.   DOI
21 Department of Pediatrics, Nationwide Korean Medicine College. Pediatrics of korean medicine. 3rd ed. Seoul: Ui Sung Dang Publishing Cooperation; 2020:751-4.
22 Jing P, Lin XD. Curative effect of Xiaoyu anshen decoction combined with Shugan jieyu capsule in treatment of adolescent depression. Chin Arch Trad Chin Med. 2016;34(6):1476-8.
23 Findling RL, McNamara NK, O'Riordan MA, Reed MD, Demeter CA, Branicky LA, Blumer JL. An open-label pilot study of St. John's wort in juvenile depression. J Am Acad Child Adolesc Psychiatry. 2003;42(8):904-8.
24 Simeon J, Nixon MK, Milin R, Jovanovic R, Walker S. Open-label pilot study of St. John's Wort in adolescent depression. J Child Adolesc Psychopharmacol. 2005;15(2):293-301.   DOI
25 Zhao SL, Hu GH. Hu Guoheng treats juvenile depression syndrome from the perspective of kidney. Chin Naturopath. 2021;29(14):20-2.
26 Li TJ, Jiang XH, Niu Z, Wang FF. Professor ma bingxiang's experience in treating depression in children and adolescents. Chin J Ethnomed Ethnopharm. 2019;28(6):49-51.
27 Liu P, Liu XP, Jin X, et al. Experience in treating children's depression from deficiency of heart and spleen. Global Trad Chin Med. 2021;14(3):488-91.
28 Butterweck V. Mechanism of action of St John's wort in depression : what is known? CNS drugs. 2003;17(8):539-62.   DOI
29 Zhang H, Zhang S, Hu M, Chen Y, Wang W, Zhang K, Kuang H, Wang Q. An integrative metabolomics and network pharmacology method for exploring the effect and mechanism of Radix Bupleuri and Radix Paeoniae Alba on anti-depression. J Pharm Biomed Anal. 2020;189(113435):1-19.
30 Linde K, Berner MM, Kriston L. St John's wort for major depression (Review). Cochrane Database Syst Rev. 2008(4):1-83.
31 Chang SM, Sohn JH, Lee JY, Choi JH, Cho SJ, Jeon HJ, Hahm BJ, Lee DH, Cho MJ. Characteristics of diagnostic criteria for depression in Korea. J Korean Neuropsychiatr Assoc. 2007;46(5):447-52.
32 Clinical Practice Guidelines Establishment Committee and Development Committee of Depression of Korean Academy of Medical Sciences. Evidence-based recommendations for depression in primary care. 1st ed. Seoul: Korean Academy of Medical Sciences, Korea Disease Control and Prevention Agency. 2021:17.
33 Chinese Society of Psychiatry. Chinese classification of mental disorders (CCMD). 3rd ed. Jinan: Chinese Society of Psychiatry. 2001:48.
34 Xing J. A preliminary study on the consistency of CCMD-3 and DSM-IV in the diagnosis of depression. Med J Chin People Health. 2015;27(7):106-7.
35 Zuckerbrot RA, Cheung A, Jensen PS, Stein RE, Laraque D, Levitt A, Birmaher B, Campo H, Clarke G, Emslie G. Guidelines for adolescent depression in primary care (GLAD-PC): Part I. practice preparation, identification, assessment, and initial management. Pediatrics. 2018;141(3):1-21.   DOI
36 Lu XL. Chinese medicine treatment of adolescent depression. Rural Know How. 2019(14):52.
37 Feng L, Zhang XY, Zhao G. Observation on the treatment of mixed anxiety and depression in children with traditional Chinese medicine combined with micro-bioelectrical induction stimulation. Chin Arch Trad Chin Med. 2016;34(8):1978-80.
38 Shi P, Liu XP, Song D. Shuganjieyu capsule combined with sertraline hydrochloride in the treatment clinical observation on first-episode depression in adolescents. J Practical Tradit Chin Med. 2020;36(6):765-6.
39 Cheung AH, Zuckerbrot RA, Jensen PS, Laraque D, Stein R, Levitt A, Birmaher B, Campo J, Clarke G, Emslie G. Guidelines for adolescent depression in primary care (GLAD-PC): part II. treatment and ongoing management. Pediatrics. 2018;141(3):1-16.   DOI
40 Qu B. A comparative study of Shuganjieyu capsules and sertraline hydrochloride in the treatment of adolescent depression. Inner Mongolia J Tradit Chin Med. 2011;30(19):67-8.
41 Birmaher B, Brent D. Practice parameter for the assessment and treatment of children and adolescents with depressive disorders. J Am Acad Child Adolesc Psychiatry. 2007;46(11):1503-26.   DOI
42 Hathaway EE, Walkup JT, Strawn JR. Antidepressant treatment duration in pediatric depressive and anxiety disorders: how long is long enough? Curr Probl Pediatr Adolesc Health Care. 2018;48(2):31-9.   DOI
43 Cala S, Crismon ML, Baumgartner J. A survey of herbal use in children with attention-deficit-hyperactivity disorder or depression. Pharmacotherapy. Feb 2003;23(2):222-30.   DOI