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http://dx.doi.org/10.7778/jpkm.2014.28.1.032

The Relationship between Allergic Diseases and Functional Gastrointestinal Disorders in Children and Adolescents  

Kim, Min Joo (Pediatrics of Clinical Korean Medicine, College of Korean Medicine, Kyung Hee University)
Kim, Deog Gon (Pediatrics of Clinical Korean Medicine, College of Korean Medicine, Kyung Hee University)
Lee, Jin Yong (Pediatrics of Clinical Korean Medicine, College of Korean Medicine, Kyung Hee University)
Publication Information
The Journal of Pediatrics of Korean Medicine / v.28, no.1, 2014 , pp. 32-42 More about this Journal
Abstract
Objectives The purpose of this study is to establish relationship between allergic diseases and functional gastrointestinal disorders in children and adolescents using objective criteria and questionnaires. Methods This study surveyed 237 children and adolescents who visited the department of Pediatrics of ${\bigcirc}{\bigcirc}$ Korean Medicine Hospital from September 23rd, 2013 to December 26th, 2013. The Korean version of International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire and the Korean-translated Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III (QPGS-Rome III) were used. We analyzed the data by using PASW Statistics 18.0 with Chi-square test, Fisher's exact test and Linear by linear association. Results There was no significant difference between prevalence of allergic diseases and functional gastrointestinal disorders. Also, there was no strong relationship between the number of allergic diseases and the functional gastrointestinal disorders. However, some parts showed significant relationships - such as asthma symptoms ever and belch; asthma symptoms last 12 months and belch; allergic rhinitis diagnosis ever and belly aches and abdominal pain around and below the belly button; allergic rhinitis treatment last 12 months and belly aches and abdominal pain around and below the belly button; and atopic dermatitis diagnosis ever and irritable bowel syndrome (respectively; p=0.046, p=0.008, p=0.004, p=0.029, p=0.035). And as the number of allergic diseases increases, the prevalence of functional gastrointestinal disorders are 19.4%, 31.3%, 41.7%, 31.0% respectively. Conclusions Although there was no significant relationship between allergic diseases and functional gastrointestinal disorders, some gastrointestinal symptoms were related to allergic diseases.
Keywords
Asthma; Allergic rhinitis; Atopic dermatitis; Functional gastrointestinal disorders; International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire; Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III (QPGS-Rome III);
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1 Ahn K, Kim J, Kwon HJ, Chae Y, Hahm MI, Lee KJ, Park YM, Lee SY, Han M, Kim WK. The prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in Korean children: Nationwide cross-sectional survey using complex sampling design. J Korean Med Assoc. 2011;54(7):769-78.   DOI   ScienceOn
2 Choi MH, Kim DG, Lee JY. A study of the Chief Complaint of Pediatric Outpatients in the Kyung Hee Oriental Medicine Hospital. J Korean Oriental Pediatr. 2010;24(3):121-37.
3 Miele E, Simeone D, Marino A, Greco L, Auricchio R, Novek SJ, Staiano A. Functional gastrointestinal disorders in children: an Italian prospective survey. Pediatrics. 2004;114(1):73-8.   DOI   ScienceOn
4 Uc A, Hyman PE, Walker LS. Functional gastrointestinal disorders in African American children in primary care. J Pediatr Gastroenterol Nutr. 2006;42(3):270-4.   DOI   ScienceOn
5 Won JB. Epidemiologic features of functional gastrointestinal disorders in Korean elementary schoolchild using Rome III questionnaire. Master of Medical Science in Pediatrics. Gachon Graduate School of Medicine. 2012:1-34.
6 Daher S, Tahan S, Solé D, Naspitz CK, Da Silva Patrício FR, Neto UF, De Morais MB. Cow's milk protein intolerance and chronic constipation in children. Pediatr Allergy Immunol. 2001;12(6):339-42.   DOI   ScienceOn
7 Asher MI, Montefort S, Björkstén B, Lai CK, Strachan DP, Weiland SK, Williams H, ISAAC Phase Three Study Group. Worldwide time trends in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis, and eczema in childhood: ISAAC Phases One and Three repeat multicountry cross-sectional surveys. Lancet. 2006;368: 733-43.   DOI   ScienceOn
8 Oh IH, Yoon SJ, Kim EJ. The burden of disease in Korea. J Korean Med Assoc. 2011;54:646-52.   DOI   ScienceOn
9 Tran NP, Vickery J, Blaiss MS. Management of rhinitis: allergic and non-allergic. Allergy Asthma Immunol Res. 2011;3:148-56.   DOI   ScienceOn
10 Li XM. Complementary and alternative medicine in pediatric allergic disorders. Curr Opin Allergy Clin Immunol. 2009;9(2):161-7.   DOI   ScienceOn
11 Hwang JS, Im SH. Probiotics as an immune modulator for allergic disorder. Pediatr Allergy Respir Dis (Korea). 2012;22:325-35.   DOI
12 Woo HS, Kim CH. The review of oriental medical therapy on allergic rhinitis. J Korean Orient Med. 2006; 27(1):155-64.   과학기술학회마을
13 Di Mauro A, Neu J, Riezzo G, Raimondi F, Martinelli D, Francavilla R, Indrio F. Gastrointestinal function development and microbiota. Italian J Pediatr. 2013;39:15.   DOI
14 Kim KB, Kim DG, Kim YH, Kim JH, Min SY, Park EJ, Baek JH, Yu SA, Lee JY, Lee HJ, Chang GT, Chai JW, Han YJ, Han JK. Hanbangsoacheongsonyeonuihak. Seoul:Ui Sung Dang publishing Co. 2010:370-7.
15 Wang DY. Junguiibiinhugwahak. Beijing:Gwahakchulpansa. 1976:275-6.
16 Caffarelli C, Deriu FM, Terzi V, Perrone F, De Angelis G, Atherton DJ. Gastrointestinal symptoms in patients with asthma. Arch Dis Child. 2000;82(2):131-5.   DOI
17 Caffarelli C, Cavagni G, Deriu FM, Zanotti P, Atherton DJ. Gastrointestinal symptoms in atopic eczema. Arch Dis Child. 1998;78(3):230-4.   DOI
18 Rokaite R, Labanauskas L. Gastrointestinal disorders in children with atopic dermatitis. Medicina (Kaunas). 2005;41(10):837-45.
19 Kim DS, Nho HN, Kim C, Lee HW, Yoon JH, Uhm JH. Diagnosis of functional gastrointestinal disorders with Rome III Criteria in korean pediatric and adolescent patients: clinical usefulness of QPGS. Korean J Pediatr Gastroenterol Nutr. 2009;12(02):120-32.   과학기술학회마을
20 Wahn U. What drives the allergic march? Allergy. 2000;55(7):591-9.   DOI   ScienceOn
21 Gordon BR. The allergic march: can we prevent allergies and asthma? Otolaryngol Clin North Am. 2011;44(3): 765-77.   DOI   ScienceOn
22 Zhong DY. Pibugwa Hanbangchiryo. Seoul:Il Jung Sa Publishing Co. 1991:68-71.
23 Choi SW, Ju YS, Kim DS, Kim JY, Kwon HJ, Kang DH, Lee SI, Cho SH. Reliability and validity of the Korean version of ISAAC questionnaire. Korean J Prev Med. 1998;31:361-71.   과학기술학회마을
24 Zheng T, Yu J, Oh MH, Zhu Z. The atopic march: progression from atopic dermatitis to allergic rhinitis and asthma. Allergy Asthma Immunol Res. 2011;3:67-73.   DOI   ScienceOn