Analysis of Factors Enhancing Growth Effect of Boyangsungjang-Tang

Objectives The purpose of this study is to analyze factors that enhance growth effect after the administration of Boyangsungjang-Tang (補陽成長湯) to children and adolescents. Methods This clinical study has been carried out with 112 children and adolescents, who visited one University Oriental Medicine Hospital Pediatric department, from January 2009 to December 2010. They were treated on height-growth with Boyangsungjang-Tang (補陽成長湯). We used modified-intend to treat analysis to examine children who had their height and weight records six months after the treatment. We use PASW Statistics 18.0 to analyze what factors (Height percentile, Weight percentile, Age, Birth weight, Frequency of taking Medicine, Period of Treatment) enhanced the growth by using t-test, one-way ANOVA, Pearson's correlation analysis. Results The mean value of the height percentile were significantly increased, $2.83{\pm}10.04$ ($36.61{\pm}27.02$ to $39.44{\pm}26.89$, P=0.004). The height percentile difference has significantly correlated with weight percentile (P<0.001) and height percentile (P<0.05). Weight less than 50 percentile (P<0.05), and treatment period more than 15 months (P<0.05) had significant impact on the height percentile differences. Conclusions If we have treated more than 15 months of Boyangsungjang-Tang (補陽成長湯) to children and adolescents whose weight are less than 50 percentile, we would have expected their height percentile to increase as $5.72{\pm}10.64$.

보양성장탕 (補陽成長湯) 투여의 성장효과를 높이는 요인 분석