Browse > Article
http://dx.doi.org/10.14406/acu.2020.008

Efficacy and Safety of Miniscalpel Acupuncture, Non-Steroidal Anti-Inflammatory Drugs or Combined Treatment for Chronic Neck Pain: An Assessor-Blinded Randomized Controlled Pilot Study  

Gong, Han Mi (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University)
Jun, Seungah (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University)
Chung, Yeon-Joong (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University)
Kim, Ju-Ran (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University)
Lee, Jung Hee (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University)
Lee, Hyun-Jong (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University)
Park, Chung A (Department of Diagnostics, College of Korean Medicine, Daegu Haany University)
Kim, Jae Soo (Department of Acupuncture & Moxibustion Medicine, College of Korean Medicine, Daegu Haany University)
Publication Information
Korean Journal of Acupuncture / v.37, no.1, 2020 , pp. 14-23 More about this Journal
Abstract
Objectives : We investigated the efficacy and safety of miniscalpel acupuncture (MA) treatment combined with non-steroidal anti-inflammatory drugs (NSAIDs) for chronic neck pain (CNP) in an assessor-blinded randomized controlled pilot trial to establish a basis for larger-scale randomized controlled studies on this subject. Methods : Participants (n=36) were recruited and randomly allocated to the MA group, NSAIDs and combined treatment group. The MA group received MA three times over three weeks. The NSAIDs group was administered orally with zaltoprofen 80mg t.i.d. over three weeks. The combined treatment group received MA and zaltoprofen in the same manner as MA and NSAIDs groups. The primary outcome was pain as assessed by a visual analogue scale (VAS) and the secondary outcomes were assessed using the Neck Disability index (NDI), EuroQol 5-dimension questionnaire (EQ-5D), and Patients' Global Impression of Change scale (PGIC). Assessments were made at week 0 (baseline), 1, 2, 3 (primary end point) during treatment and at week 7 (4 weeks after the end of treatment). Results : 35 participants completed the study. No serious adverse event occurred and blood test results were within normal limits. The improvement of VAS and NDI was significantly greater in combined and MA group than that in NSAIDs group (p<0.017). The combined group showed better outcomes in EQ-5D at visit 2 and 5, in PGIC at visit 4 than the NSAIDs group (p<0.017). No significant differences were found between combined and MA group. Conclusions : Our results suggest that both combined and MA group can be more effective in improving pain control than NSAIDs group. A large-scale clinical study is warranted to further clarify these findings.
Keywords
chronic neck pain; miniscalpel acupuncture; non-steroidal anti-inflammatory drugs; pilot study; VAS;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
연도 인용수 순위
1 Aker PD, Gross AR, Goldsmith CH, Peloso P. Conservative management of mechanical neck pain: systematic overview and meta-analysis. BMJ. 1996 ; 313(7068) : 1291-6. https://doi.org/10.1136/bmj.313.7068.1291   DOI
2 Bjarnason I, Hayllar J, MacPherson AJ. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology. 1993 ; 104(6) : 1832-47. https://doi.org/10.1016/0016-5085(93)90667-2   DOI
3 HIRA[Internet]. National health insurance statistical yearbook : 2019 July 24. [cited 2020 Feb 26]. Available from:URL:https://opendata.hira.or.kr/op/opc/selectStcPblcList.do?odPblcTpCd=002
4 Kim JR, Lee JH, Gong HM, Jun S, Chung Y, Park CA, et al. Miniscalpel acupuncture points of the cervical region: a review. J Acupunct Res. 2017 ; 34(3) : 91-100. http://dx.doi.org/10.13045/acupunct.2017095   DOI
5 Liang Z, Zhu X, Yang X, Fu W, Lu A. Assessment of a traditional acupuncture therapy for chronic neck pain: a pilot randomised controlled study. Complement Ther Med. 2011 ; 19 Suppl 1 : S26-32. https://doi.org/10.1016/j.ctim.2010.11.005   DOI
6 Park JY, Yun KJ, Choi YJ, Kim MS, Jeon JC, Lee TH, et al. Comparative study of treatment effect between near acupuncture point needling and near acupuncture with remote acupuncture point needling on treatment of posterior neck pain. J Acupunct Res. 2011 ; 28(1) : 85-92.
7 Cote P, Cassidy JD, Carroll LJ, Kristman V. The annual incidence and course of neck pain in the general population: a population-based cohort study. Pain. 2004 ; 112(3) : 267-73. https://doi.org/10.1016/j.pain.2004.09.004   DOI
8 Yalcinkaya H, Ucok K, Ulasli AM, Coban NF, Aydin S, Kaya I, et al. Do male and female patients with chronic neck pain really have different health-related physical fitness, depression, anxiety and quality of life parameters? Int J Rheum Dis. 2017 ; 20(9) : 1079-87. https://doi.org/10.1111/1756-185X.12389   DOI
9 Hoy D, Protani M, De R, Buchbinder R. The epidemiology of neck pain. Best Pract Res Clin Rheumatol. 2010 ; 24(6) : 783-92. https://doi.org/10.1016/j.berh.2011.01.019   DOI
10 Fejer R, Kyvik KO, Hartvigsen J. The prevalence of neck pain in the world population: a systematic critical review of the literature. Eur Spine J. 2006 ; 15(6) : 834-48. https://doi.org/10.1007/s00586-004-0864-4   DOI
11 Guo C, Liu N, Li X, Sun H, Hu B, Lu J, et al. Effect of acupotomy on nitric oxide synthase and beta-endorphin in third lumbar vertebrae transverse process syndrome model rats. J Tradit Chin Med. 2014 ; 34(2) : 194-8. https://doi.org/10.1016/s0254-6272(14)60078-9   DOI
12 Carlsson AM. Assessment of chronic pain. I. aspects of the reliability and validity of the visual analogue scale. Pain. 1983 ; 16(1) : 87-101. https://doi.org/10.1016/0304-3959(83)90088-x   DOI
13 Lee G, Kim D, Kim H, Yeom S, Kim H, Kim D, et al. The study on the effect of acupotomy in lumbar HIVD. J Acupunct Res. 2008 ; 25(4) : 183-90.
14 Morikawa Y, Takamoto K, Nishimaru H, Taguchi T, Urakawa S, Sakai S, et al. Compression at myofascial trigger point on chronic neck pain provides pain relief through the prefrontal cortex and autonomic nervous system: a pilot study. Front Neurosci. 2017 ; 11 : 186. https://doi.org/10.3389/fnins.2017.00186   DOI
15 Munoz-Munoz S, Munoz-Garcia MT, Alburquerque-Sendin F, Arroyo-Morales M, Fernandez-de-las-Penas C. Myofascial trigger points, pain, disability, and sleep quality in individuals with mechanical neck pain. J Manipulative Physiol Ther. 2012 ; 35(8) : 608-13. https://doi.org/10.1016/j.jmpt.2012.09.003   DOI
16 Vernon H, Mior S. The neck disability index: a study of reliability and validity. J Manipulative Physiol Ther. 1991 ; 14(7) : 409-15.
17 Obradovic M, Lal A, Liedgens H. Validity and responsiveness of EuroQol-5 dimension (EQ-5D) versus short form-6 dimension (SF-6D) questionnaire in chronic pain. Health Qual Life Outcomes. 2013 ; 11(1) : 110. https://doi.org/10.1186/1477-7525-11-110   DOI
18 Amirfeyz R, Pentlow A, Foote J, Leslie I. Assessing the clinical significance of change scores following carpal tunnel surgery. Int Orthop. 2009 ; 33(1) : 181-5. https://doi.org/10.1007/s00264-007-0471-1   DOI
19 Wang WT, Olson SL, Campbell AH, Hanten WP, Gleeson PB. Effectiveness of physical therapy for patients with neck pain: an individualized approach using a clinical decision-making algorithm. Am J Phys Med Rehabil. 2003 ; 82(3) : 203, 18 ; 219-21. https://doi.org/10.1097/01.PHM.0000052700.48757.CF
20 Lee HE, Lee EJ, Oh MS. Systematic Review of Selection of Acupoints in Domestic Clinical Studies Related to Nuchal Pain. J Physiol & Pathol Korean Med. 2013 ; 27(6) : 698-704. https://doi.org/10.15188/kjopp.2013.12.27.6.698
21 Brodsky M, Spritzer K, Hays RD, Hui K. Change in health-related quality-of-life at group and individual levels over time in patients treated for chronic myofascial neck pain. J Evid Based Complementary Altern Med. 2017 ; 22(3) : 365-8. https://doi.org/10.1177/2156587216662779   DOI
22 Vas J, Perea-Milla E, Mendez C, Navarro CS, Rubio JML, Brioso M, et al. Efficacy and safety of acupuncture for chronic uncomplicated neck pain: a randomised controlled study. Pain. 2006 ; 126(1-3) : 245-55. https://doi.org/10.1016/j.pain.2006.07.002   DOI
23 Kim E, Kim H, Lee G, Lee G. The clinical study on effects of acupotomy therapy in patients with cervical herniated intervertebral disc. J Acupunct Res. 2009 ; 26(1) : 67-79.
24 Park S, Kim S, Yang S, Lee G. The clinical effects of acupotomy for ossification of the posterior longitudinal ligament. J Acupunct Res. 2011 ; 28(4) : 127-35.
25 Ma C, Wu S, Li G, Xiao X, Mai M, Yan T. Comparison of miniscalpelneedle release, acupuncture needling, and stretching exercise to trigger point in myofascial pain syndrome. Clin J Pain. 2010 ; 26(3) : 251-7. https://doi.org/10.1097/AJP.0b013e3181b8cdc8   DOI
26 Zheng Y, Shi D, Wu X, Gu M, Ai Z, Tang K, et al. Ultrasound-guided miniscalpel-needle release versus dry needling for chronic neck pain: A randomized controlled trial. Evid Based Complement Alternat Med. 2014 ; 2014 : 235817. https://doi.org/10.1155/2014/235817
27 Li S, Shen T, Liang Y, Zhang Y, Bai B. Effects of miniscalpel-needle release on chronic neck pain: a retrospective analysis with 12-month follow-up. PLoS One. 2015 ; 10(8) : e0137033. https://doi.org/10.1371/journal.pone.0137033   DOI