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http://dx.doi.org/10.14406/acu.2014.032

The Study on Pharmacological Activation as Cosmetic Material of Rosa rugosa Thunb. Flowers Extract  

Yu, Hye-Soo (Department of Beauty Design School, Wonkwang University)
Choi, Ji-Eun (BK21-plus Team, Professional Graduate School of Oriental Medicine, Wonkwang University)
Woo, Won-Hong (Department of Anatomy, College of Oriental Medicine, Wonkwang University)
Mun, Yeun-Ja (BK21-plus Team, Professional Graduate School of Oriental Medicine, Wonkwang University)
Publication Information
Korean Journal of Acupuncture / v.31, no.4, 2014 , pp. 188-194 More about this Journal
Abstract
Objectives : In this study, we investigated the effect of ethanol extract from Rosa rugosa Thunb. flowers(ERF) on the activities of antioxidant, antiwrinkle and whitening. Methods : We measured antioxidant efficacy of ERF by using 1,1-diphenyl-2-picrylhydrazyl(DPPH) assay. Also we confirmed the inhibitory effect of ERF on collagenase activity and melanin synthesis by using collagenase assay kit and dihydroxiphenylalanine staining, respectively. To evaluate the anti-inflammatory effects of ERF, we examined the inflammatory mediator IL-6. Results : ERF showed highly efficacy in DPPH radical scavenging activity. ERF dose-dependently suppressed collagenase activity. Ultraviolet-induced production of IL-6 decreased by ERF treatment. In B16F10 cell, ERF significantly reduced tyrosinase activity and melanin synthesis. Conclusions : From the above results, it was indicated that ERF could be utilized as anti-aging and whitening cosmetic ingredients.
Keywords
Rosa rugosa Thunb flowers; antioxidant; collagenase; melanin;
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Times Cited By KSCI : 5  (Citation Analysis)
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