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http://dx.doi.org/10.9713/kcer.2018.56.2.245

Antibacterial and Whitening Activities of Coffea arabica Ethanol Extract  

Kim, In Hae (Department of Pharmaceutical Engineering, College of Medical & Life Science, Silla University)
Lee, Jae Hwa (Department of Pharmaceutical Engineering, College of Medical & Life Science, Silla University)
Publication Information
Korean Chemical Engineering Research / v.56, no.2, 2018 , pp. 245-251 More about this Journal
Abstract
In this study, Coffea arabica ethanol extract (CAE) was tested for possible functional cosmetic agent. Whitening effect was measured by tyrosinase inhibition assay, and anti-oxidant activity was checked by SOD-like activity. SOD-like activity of CAE showed $94.8{\pm}6.2%$ at $500{\mu}g/mL$. The anti-bacterial activities CAE was evaluated against three different gram-positive bacteria and six gram-negative bacteria including MRSA strains. CAE exhibited in vitro broad spectrum antimicrobial activities of gram-negative bacteria without antifungal activity. CAE was strong exhibited against MRSA CCARM3561. The tyrosinase and L-DOPA inhibitory activities of the CAE lower than those positive control arbutin. CAE reduced melanin contents of B16-F10 melanoma cell in a dose dependent manner and decrease about 89.2% at a concentration $100{\mu}g/mL$. These result highlight the potential of coffee extract as a naturally active and non-toxic antibacterial suitable for cosmetic applications.
Keywords
Coffea arabica; Cosmetic; MRSA; Tyrosinase; Melanin synthesis;
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Times Cited By KSCI : 4  (Citation Analysis)
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